Acute respiratory infections represent a significant cause of over-prescription of antibiotics and are one of the major reasons for absence from work. The leaves of Andrographis paniculata (Burm. f.) Wall ex Nees (Acanthaceae) are used as a medicinal herb in the treatment of infectious diseases. Systematic literature searches were conducted in six computerised databases and the reference lists ...

Exploration of herbs combination could be an alternative way for developing traditional medicine in order to provide better result or benefits in the therapy of diseases. Andrographis paniculata (Burm. f.) Ness and Gynura procumbens (Lour.) Merr are two medicinal plants that are already well known for traditional treatment of diabetes mellitus (DM). Combination of potent hypoglycaemic effect of...

background: the aim of the present study was to evaluate the radioprotective effect of grewia asiatica fruit pulp extract (gae) on swiss albino mice exposed to gamma radiation. in the present study radioprotective efficacy of grewia asiatica (rich in anthocyanin, carotenes, vitamin c, etc.) was studied against radiation induced biochemical alterations in mice cerebrum. materials and methods: fo...

BACKGROUND The anti-inflammatory activity of Andrographis paniculata (Acanthaceae), a traditional medicine widely used in Asia, is commonly attributed to andrographolide, its main secondary metabolite. Commercial A. paniculata extracts are standardised to andrographolide content. We undertook the present study to investigate 1) how selective enrichment of andrographolide in commercial A. panicu...

Andrographis paniculata has been used as a traditional medicine and a predominant constituent in 26 Ayurvedic formulations over the last two decades. Its impact on the male fertility is a controversial from the past few years. In the present study we have investigated the antioxidant enzyme status and the indices of lipid peroxidation in the testis and epididymis of male wistar rats. Male wista...

Quantitative and qualitative improvement of rare and valuable bioactive plant products is promisingly possible using In-vitro cell culture techniques. The present investigation was conducted with the aim to elicit the synthesis of andrographolide by subjecting cultured cells of Andrographis paniculata to Salicylic acid (SA) and Chitosan mediated abiotic stress Cell suspension culture of Androgr...

Fresh leaves of Boerhaavia diffusa and Andrographis paniculata were evaluated for nutritional and anti-nutritional compositions. The results showed that both plant leaves contained saponins, alkaloids and flavonoids. The proximate analysis and vitamin C of B. diffusa and A. paniculata included moisture (76.04% and 73.02%), carbohydrate (17.14% and 12.16%) and vitamin C (40.00 and 45.01mg/100g),...

This study evaluated the action of Pfaffia paniculata K., Juglans regia L., and Rosmarius officinalis L. extracts against planktonic form and biofilm of Klebsiella pneumoniae (ATCC 4352). Minimum inhibitory concentration (MIC) and minimum microbicidal concentration (MMC) values were determined for each extract by microdilution broth method, according to Clinical and Laboratory Standards Institu...

The integration of Andrographis paniculata under Pinus roxburghii (Chir pine) plantation has been studied to evaluate the growth and yield for its economic viability and conservation. It was grown on three topographical aspects, namely, northern, north-western, and western, at a spacing of 30 cm × 30 cm, followed by three tillage depths, namely, minimum (0 cm), medium (up to 10 cm), and deep (u...

The effects of Andrographis paniculata and Orthosiphon stamineus extracts on the in vitro glucuronidation of 4-methylumbelliferone (4MU) by recombinant human UGTs, UGT1A1, UGT1A3, UGT1A6, UGT1A7, UGT1A8, UGT1A10, UGT2B7 and UGT2B15 were determined. The potential inhibitory effects of both of the extracts on the activity of each of the UGT isoforms were investigated using 4MU as the substrate. I...