This experiment explored the relationship between neural firing patterns in second somatosensory cortex (SII) and decisions about roughness of tactile gratings. Neural and behavioral data were acquired while monkeys made dichotomous roughness classifications of pairs of gratings that differed in groove width (1.07 vs. 1.90 and 1.42 vs. 2.53 mm). A computer-controlled device delivered the gratin...

The double-stranded DNA of the genome contains both sequence information directly relating to the protein and RNA coding as well as functional and structural information relating to protein recognition. Only recently is the importance of DNA shape in this recognition process being fully appreciated, and it also appears that minor groove electronegative potential may contribute significantly in ...

Pax proteins are a family of transcription factors conserved during evolution and able to bind specific DNA sequences through a domain called a "paired domain'. The DNA-binding specificity of the Pax-8 paired domain was investigated. Site-selection experiments indicate that Pax-8 binds to a consensus sequence similar to those bound by Pax-2 and Pax-5. When consensus sequences of various paired ...

Abstract We delineate the four principal surface plasmon polariton coupling and interaction mechanisms in subwavelength gratings, demonstrate their significant roles shaping optical response of plasmonic gratings. Within framework width-graded metal–insulator-metal nano-gratings, electromagnetic field confinement wave guiding result multiwavelength light localization provided conditions adiabat...

Background: Pancreatic groove cancer is very rare and could be masqueraded as pancreatitis. This study to clarify the characteristics, clinical features, managements survival outcomes of this tumor. Methods: Brief descriptions were made for each case pancreatic encountered at our institute. Individualized data cases described in literature extracted added database expand sample size a more comp...