نتایج جستجو برای: haack series
تعداد نتایج: 351102 فیلتر نتایج به سال:
Design of experiments (DOE) methodology was used to identify and optimize factors that influence the degree of functionalization (polycarboxylation) of WS2 INTs via a modified acidic Vilsmeier–Haack reagent. The six factors investigated were reaction time, temperature and the concentrations of 2-bromoacetic acid, WS2 INTs, silver acetate and DMF. The significance of each factor and the associat...
It is widely held, to the point of being the received interpretation, that Frank Ramsey was the first to defend the so-called Redundancy Theory of Truth in his landmark article ‘Facts and Propositions’ (hereafter ‘FP’) of 1927. For instance, A.J. Ayer cited this article in the context of arguing that saying that p is true is simply a way of asserting p and that truth is not a real quality or re...
Mycobacterium tuberculosis FabH, an essential enzyme in the mycolic acid biosynthetic pathway, is an attractive target for novel anti-tubercolosis agents. Structure-based design and synthesis of 1-(4-carboxybutyl)-4-(4-(substituted benzyloxy)phenyl)-1H-pyrrole-2-carboxylic acid derivatives 7a-h, a subset of eight potential FabH inhibitors, is described in this paper. The Vilsmeier-Haack reactio...
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