background: the pathogenesis of nontypeable haemophilus influenzae (nthi) begins with adhesion to the rhinopharyngeal mucosa. almost 38-80% of nthi clinical isolates produce proteins that belong to the high molecular weight (hmw) family of adhesins, which are believed to facilitate colonization. methods: in the present study, the prevalence of hmwa, which encodes the hmw adhesin, was determined...

BACKGROUND AND OBJECTIVE Haemophilus influenzae type b (Hib) is divided into two distinct genotypes, type I and type II, based on the structure of capsular polysaccharides. The capsulation locus of Haemophilus influenzae type b consists of three functionally distinct regions, designated regions 1 to 3. Region III contains hcsA and hcsB genes; however, notable sequence variation in this region c...

Background: Streptococcus pneumoniae and Haemophilus influenzae type b (Hib) is a leading cause of bacterial pneumonia, meningitis, and sepsis in children under 5-year of age. This study aims to estimate potentially preventable number of cases and deaths caused by Hib and pneumococcal in Iran.Materials and Methods:We used the burden of diseases model estimates of the World Health Organization (...

Encephalitis is the inflammation of brain which usually caused by viral infections, but it can be also due to other non-infectious agents. We report an interesting case anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis with Haemophilus influenzae co-infection in association severe acute respiratory syndrome coronavirus 2, without pulmonary involvement or fever.

  Introduction : Haemophilus influenzae is a gram-negative bacterium causing a variety of respiratory infections in developing countries, especially in children. Nasopharynx carriers of H. influenzae are the prominent source and transitional vectors of invasive diseases. As very limited information on H. influenzae carriage rate in Iran was available, an evaluation on prevalence of this bacteri...

in children. although its burden is considerably preventable by vaccine, routine vaccination against hib has not been defined in the national immunization program of iran. this study was performed to assess the cost-benefit and cost‑utility of running an hib vaccination program in iran. methods: based on a previous systematic review and meta‑analysis for vaccine efficacy, we estimated the avert...

background outer membrane protein d (pd) is a highly conserved and stable protein in the outer membrane of both encapsulated (typeable) and non-capsulated (non-typeable) strains of haemophilus influenzae. as an immunogen, pd is a potential candidate vaccine against non-typeable h. influenzae (nthi) strains. objectives the aim of this study was to determine the cytokine pattern and the opsonic a...

The complete capsule (cap) loci from three Haemophilus influenzae strains, one serotype b (Hib) and two nonencapsulated b capsule-negative variants, were sequenced. Two new open reading frames, hcsA and hcsB, were identified in region III and thought to be involved in postpolymerization modification of the capsule. The location of the cap locus in the Haemophilus influenzae chromosome was ident...

Five tests--satellitism, synthesis of porphyrins, acid production from sucrose, beta-galactosidase activity (ONPG), and indole production--to differentiate between strains of Haemophilus influenzae and strains of V-dependent Haemophilus species were evaluated. Six per cent of strains of H influenzae were misidentified as H parainfluenzae by a test for satellitism using filter paper discs impreg...

Partnerships are at the center of the Hospital of the University of Pennsylvania Nursing Excellence Professional Practice (HUP-NEPP) model. Through the use of collaboration, skilled communication, and respectful workplace, partnerships can be formed, leading ultimately to world-class patient care. At HUP, interdisciplinary partnerships are evidenced by the clinical nurses through shared governa...