Hidradenitis suppurativa, dissecting cellulitis of the scalp, acne conglobata and pilonidal sinus ― are four diseases united by similar clinical findings common mechanisms pathogenesis. These conditions often coexist. The primer pathogenetic event is stratum corneum thickening keratin plugging hair follicle ductal isthmus. discovery this mechanism led to association all with term "follicular oc...

There exist some restrictions and difficulties in performing follicular unit extraction (FUE) in white-haired patients, for several reasons. In this paper, we introduce a novel technique for visualizing white hair during the punching procedure and graft preparation in FUE for white-haired patients. In white-haired older male patients, we dyed the surrounding scalp skin purple with a gentian vio...

androgenetic alopecia is the most common form of hair loss in men. the present study was designed to evaluate the hair growth-promoting activity of a preparation of the adiantum capillus veneris linn. (a. capillus veneris linn.) on albino mice using a testosterone-induced alopecia model. five groups of albino mice were studied: (a) testosterone solution only (n=6); (b) testosterone ‏+ finasteri...

Notch signaling plays an important role in hair follicle maintenance, and it has been suggested that Notch is also required for follicular fate selection by adult hair follicle stem cells in the bulge. Here we demonstrate that, on the contrary, Notch signaling in bi-potential bulge stem cells or their uncommitted descendents acts to suppress the epidermal fate choice, thus ensuring follicular f...

Pachyonychia congenital (PC) is a rare genodermatosis affecting the nails, skin, oral mucosae, larynx, hair, and teeth. General clinical presentation includes thickening of finger and toenails, painful plantar keratoderma, hyperhidrosis, oral leukokeratosis, follicular keratosis, palmar keratoderma, cutaneous cysts, hoarseness, twisted hair and prenatal or natal teeth. Clinically, PC is d...

a case of an interesting previously unreported mixed adnexal tumor of the scalp of a 38 year old man is presented, which was composed of randomly dispersed areas of trichofolliculoma, trichoepithelioma, and pilomatricoma concomitantly. while these lesions are classified under adnexal tumors with differentiation towards hair follicle structures, controversy is present concerning the exact origin...

Eclipta alba (L.) Hassk (E. alba) is a traditionally acclaimed medicinal herb used for the promotion of hair growth. However, to the best of our knowledge, no report has been issued to date on its effects on genetically distorted hair follicles (HFs). In this study, we aimed to identify an agent (stimuli) that may be beneficial for the restoration of human hair loss and which may be used as an ...

A group of specialized mesenchymal cells located at the root of the mammalian hair follicle, known as the follicular or dermal papillary cells, are involved in regulating the hair cycle, during which keratinocytes of the lower follicle undergo proliferation, degeneration and regrowth. Using the arbitrarily primed-PCR approach, we have identified a 1.3 kb messenger RNA that is present in large q...

Techniques in hair transplantation have evolved recently which make results look more natural. Hair restoration is one of the most exciting and innovative surgical fields in aesthetic surgery today. A precise appreciation of anatomy has allowed the use of follicular unit grafts. With better methods of harvesting and implantation, hair transplantation results represent a blend of art and science.