Objectives: To assess the antibody level against hepatitis B surface antigen (anti-HBs) among newborns and their mothers and among recently vaccinated infants at age of 9 and 12 months. It also aimed at assessing the long-term immunity to hepatitis B among vaccinated children aged 6–11 years according to Egyptian expanded immunizing protocol. Methodology: Total no of 323 vaccinated healthy infa...

objective: to compare immunogenicity of a recombinant hepatitis b (hb) vaccine in two groups of neonates born in two cities of iran with different geographic and ethnic backgrounds.   materials and methods: ten micrograms of a recombinant hb vaccine was administered under field condition to iranian healthy neonates at 0, 1.5 and 9 months intervals. the subjects consisted of two groups of 290 an...

To examine the effects of drinking on liver injury in anti-hepatitis C virus (HCV)-positive subjects, 3,062 HBs-negative subjects were divided into 9 groups according to anti-HCV-titer (second-generation passive hemagglutination) and alcohol intake. Serum alanine aminotransferase (ALT) or aspartate aminotransferase (AST) levels were analyzed by multiple-comparison test. In 2,826 anti-HCV-negati...

conclusions this study shows lower anti-hbs among students who were vaccinated at infancy compared to those vaccinated at older childhood or adolescence. also, subsequent measurement of anti-hbs level at the time of entrance to university is recommended for all previously immunized students. results vaccination coverage rates were 74.1%. about half the participants didn’t show serological evide...

Hepatitis B vaccine has been available worldwide since the mid-1980s. This vaccine was evaluated in a clinical trial in Thailand, conducted on subjects born to hepatitis B surface antigen positive and hepatitis B e-antigen positive mothers and vaccinated according to a 4-dose schedule at 0, 1, 2 and 12 mo of age and a single dose of hepatitis B immunoglobulin concomitantly at birth. All enrolle...

The aim of this study was to evaluate, in adults, the immunogenicity of six hepatitis B vaccines with different doses or different manufacturers in the Chinese market and to provide evidence to support adult hepatitis B vaccination. Participants were randomly divided into six groups (I-VI). Six vaccines (4 at 10 μg/dose and 2 at 20 μg/dose) were administered intramuscularly to healthy adults at...

BACKGROUND It is important to differentiate whether isolated anti-HBc is due to false positive results or the prior exposure to hepatitis B virus, because individuals with false-positive anti-HBc can benefit from vaccination and their blood can be safely transfused. To distinguish between these two conditions, we evaluated the serologic response to hepatitis B vaccine. METHODS Ninety subjects w...

BACKGROUND Despite the advances in the treatment of chronic hepatitis B virus (HBV) infection, liver transplantation (LT) remains the only hope for many patients with end-stage liver diseases resulting from HBV. OBJECTIVES The aim of this study was to investigate the rate of HBV recurrence in cases that had undergone LT due to the HBV related liver cirrhosis. PATIENTS AND METHODS Forty-nine...

Methods: Treatment naive CHC patients were enrolled. They were classified into 2 groups according to presence or absence of PHT. Patients were subjected to liver function tests (LFTs), hepatitis C virus antibody (HCV-Ab), hepatitis B surface antigen (HBs-Ag), anti-nuclear antibody (ANA), Bilharzial agglutination titer, ultrasound abdomen and oesophago-gastro-duodensocpy. Egy-Score, ASTto-Platel...