context primary liver cancer is one of the most common and deadly malignant neoplasms worldwide. the incidence and mortality rates for hepatocellular carcinoma (hcc) are virtually identical, reflecting the poor overall survival of patients with this kind of tumor. effective therapies mostly achieved if the hcc diagnosis is made at early stages of the tumor. surveillance tests include serologic ...

context studies on experimental animals have shown liver is a common target of chemical carcinogens; this might suggest that occupational exposure to chemicals is another risk factor for hcc. however, the relationship between occupation and liver cancer has not been extensively studied, with the exception of the known association between vinyl chloride and angiosarcoma of the liver. evidence ac...

context several risk factors play the role in the development of hepatocellular carcinoma (hcc) from which chronic hepatitis b and c infections are the most important ones. dna integration of hepatitis viruses alters the function of critical genes promoting malignant transformation of virus-infected liver cells. evidence acquisition there are remarkable geographic differences in prevalence of c...

conclusion due to the significant improvement in the treatment of early stage of hcc compared to the previous decade, we suggest a fast, non-invasive, more accurate, but more expensive method (haste, op/ip t1w sequences mri combined with dwi) rather than us for the screening of hcc in liver cirrhosis. results combination of limited sequences mri and dwi had the highest accuracy (94.79%) followe...

â  â  hepatocellular carcinoma (hcc) is a major worldwide public health concern. despite recent advances, there has been little success in improving the survival of hcc patients. due to advances in diagnostic modalities and the increasing incidence of chronic viral hepatitis and nonalcoholic fatty liver disease (nafld), both of which are well known risk factors of hcc, the prevalence of hcc is ...

Hepatocellular carcinoma (HCC) is a major cause of cancer-related death worldwide. Understanding the pathogenesis HCC has significantly improved in past few years due to advances genetics, molecular biology and pathology. Several subtypes have been identified with different backgrounds outcomes, leading possible changes disease management challenging role imaging. Indeed, despite its pivotal di...

Aims: to evaluate the accuracy of LR-5 category from latest Contrast-Enhanced Ultrasound algorithm (ACR CEUS LI-RADSv 2017) for noninvasive diagnosis hepatocellular carcinoma (HCC), in a real-life cohort high-risk patients. Material and methods: We retrospectively re-analysed studies 464 focal liver lesions (FLL) 382 patients at HCC (liver cirrhosis any aetiology, chronic B or C hepatitis with ...

conclusions hbv and hcv are important culprits of hcc in emro countries and the middle east and different nations need different strategies to tackle them accordingly. countries with high rates of hbv such as turkey should continue their hbv vaccination and also increase sanitation. nations with high hcv rates such as egypt should maintain their blood product monitoring in addition to increased...

Background and Aim: Although cirrhosis is a classical risk factor for the development of hepatocellular carcinoma (HCC), its absence does not exclude this risk. We aimed to assess clinical characteristics outcomes cirrhotic HCC (C-HCC) non-cirrhotic (NC-HCC) patients. Methods: Patients consecutively included in prospective cohort (University Hospital Bern) were analysed. They categorised into t...

context hepatocellular carcinoma (hcc) is one of the most common cancers in the world but with a striking geographical variation in incidence; most of the burden is in developing countries. this geographic variation in hcc incidence might be due to geographic differences in the prevalence of various etiological factors. evidence acquisition here, we review the epidemiological evidence linking d...