Intr Mortality among leukemia patients admitted to the intensive care unit remains high [1] and bleeding complications are common in particular among thrombocytopenic patients [2]. Platelet levels measured in thrombocytopenic ICU patients reflect both the inherit and transfused platelets. ICU patients generally receive a high amount of transfusions [3] and hematological ICU patients are no exce...

Introduction: Intoxication with Sodium valproate (SVP) is a growing concern owing to its increased use and availability. SVP intoxication may result in cerebral, cardiovascular, respiratory, gastrointestinal, and hematological complications. However, SVP use does not seem to be associated with significant cardiovascular effects and electrocardiographic (ECG) abnormalities. Thus, we aimed to des...

OBJECTIVE Detailed analyses of clinical characteristics of myocardial infarction (MI) as an essential thrombocythemia (ET)- and polycythemia vera (PV)-related complication have been so far presented mostly as case reports. Therefore, the aim of this retrospective analysis was to evaluate the main cardiological and hematological characteristics for better understanding myocardial complications i...

Tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193), a selective inhibitor of the activity of IMP dehydrogenase (EC 1.1.1.205), the rate-limiting enzyme of de novo GTP biosynthesis, provided in end stage leukemic patients a rapid decrease of IMP dehydrogenase activity and GTP concentration in the blast cells and a subsequent decline in blast cell count. Sixteen consecutive pat...

In recent years, there has been renewed interest in hematological parameters as predictors of endothelial dysfunction and inflammation. The aim of our study is to evaluate the relationship between HbA1c and hematological indices, and to evaluate the relationship between these parameters and microvascular complications of diabetes. Three hundred and seven diabetic patients (124 male, 183 female;...

Hemoglobinopathies are among the most common inherited diseases around the world. Neurological manifestations in hemoglobinopathies may range from mild symptoms to serious complications. Early diagnosis and proper management of the basic disease require specialised hematological experties. In this review we discuss the current neurological manifestations, the management and prevention.

Nitrous oxide, a commonly used agent in the dental and anesthesia practice, carries serious risks to healthcare providers. Complications from its exposure can range from hematological abnormalities and neurological deficits to increased risk of spontaneous abortions in women. A concentrated effort by all anesthesia personnel is necessary to prevent the adverse effects associated with the use of...

Tiazofurin (2-/3-i>-ribofuranosylthiazole-4-carboxamide, NSC 286193), a selective inhibitor of the activity of IMP dehydrogenase (EC 1.1.1.205), the rate-limiting enzyme of de novo GTP biosynthesis, provided in end stage leukemic patients a rapid decrease of IMP dehydrogenase activity and GTP concentration in the blast cells and a subsequent decline in blast cell count. Sixteen consecutive pati...

The objective : to study the prognostic significance of ratio absolute number neutrophils lymphocytes (NLR) and platelets (PLR) in assessing risk cardiovascular complications non-cardiac surgical interventions. Subjects Methods . 85 patients aged 66 [61‒70] years who underwent elective vascular surgery were examined. Results Concomitant circulatory diseases diagnosed 98.8%. PLR < 91.2 with s...

conclusions the incidence of ipa in allogeneic hsct and patients with hematological malignancies was relatively high and a. flavus was the most common cause of pa. as molecular methods had higher sensitivity, it may be useful as screening methods in hsct and patients with hematological malignancies, or to determine when empirical antifungal therapy can be withheld. results seven (15.2%) out of ...