نتایج جستجو برای: hemoglobin oxygen saturation
تعداد نتایج: 295909 فیلتر نتایج به سال:
1. When formaldehyde (0.10 M) is added to solutions of human hemoglobin, the oxygen affinity of the hemoglobin increases considerably (more than tenfold near pH 7). The interaction between hemes of the same hemoglobin molecule decreases, as shown by a drop in the value of n in Hill's equation from 2.9 to 1.5 or less. 2. In the presence of formaldehyde, both n and the oxygen pressure for half-sa...
mean values for Po2 of 58, 60, and 72 mm Hg, respectively, were found for the three groups. When the same patients breathed oxygen via a nasal cannula or face mask at flow rates of 8 to 12 L/min, values were 106, 128, and 160 mm Hg, respectively. In all instances hemoglobin saturation values in excess of 95% were obtained when the patient breathed oxygen. In 15 patients measurements of the oxyg...
The contribution of water to the quantitative determination of hemoglobin concentration and saturation by near-infrared spectroscopy in turbid media was investigated. The study consisted of in vitro measurements of an aqueous suspension containing Liposyn, bovine blood, and yeast buffered at pH 7.2. The optical coefficients of the medium (ma;0.03 to 0.08 cm −1, ms8 ; 6 cm −1 at wavelengths of 7...
Erythrocytosis without clinical illness was noted in a man and his two daughters. Their blood contained approximately 62% hemoglobin A and 38% a new hemoglobin, designated hemoglobin Yakima. The oxygen affinity of whole blood from each subject was greatly increased and heme-heme interactions were impaired. At 37 degrees C and a plasma pH of 7.40, the oxygen pressure required to produce 50% satu...
In an effort to study the rheologic effects of small amounts of hemoglobin S (HbS) polymer in sickle red cells, we have used the ektacytometer, a laser diffraction couette viscometer, to measure sickle cell deformability as a function of oxygen tension. Sickle cell populations of defined intracellular hemoglobin concentration (MCHC) were isolated using Stractan density gradients and were resusp...
Normal and sickle erythrocytes were exposed in vitro to millimolar concentrations of 31 different carbonyl compounds. Schiff base (imine) linkages were formed with amino groups of intracellular hemoglobin. Adducts were isolated by gel electrofocusing and could be dissociated by dialysis. Aromatic aldehydes proved more reactive than aliphatic aldehydes, and ketones were unreactive. The influence...
Using transcranial cerebral oximetry, we monitored 30 patients who underwent cerebral angiography by the femoral route. Transcranial cerebral oximetry is a noninvasive technique of regional cerebral oxygen saturation measurement that uses near-infrared spectroscopy to differentiate oxyhemoglobin from reduced hemoglobin. Needle puncture, catheterization, and contrast media injection produced no ...
We develop a clinical visible-light spectroscopy (VLS) tissue oximeter. Unlike currently approved near-infrared spectroscopy (NIRS) or pulse oximetry (SpO2%), VLS relies on locally absorbed, shallow-penetrating visible light (475 to 625 nm) for the monitoring of microvascular hemoglobin oxygen saturation (StO2%), allowing incorporation into therapeutic catheters and probes. A range of probes is...
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