Common variable immunodeficiency is a primary immunodeficiency disease characterized by reduced serum immunoglobulins and heterogeneous clinical features. Recurrent pyogenic infections of upper and lower respiratory tracts are the main clinical manifestations of common variable immunodeficiency. Hemolytic uremic syndrome is a multisystemic disorder characterized by thrombocytopenia, microangiop...

Thrombotic Thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathic disease, associated with thrombocytopenia and hemolytic anemia. It is caused by an enzymatic dysfunction responsible in cleavage of blood clotting factors. In this study we have tried to review the available approaches in diagnoses of the disease as well as treatment strategies. Based on the what the current review ...

Kimura’s disease (KD) is a rare chronic inflammatory disorder that involves the lymph nodes, skin, kidneys and ears, but its influence on the hematologic system remains unknown. We discovered a rare case of KD that developed hemolytic anemia. Erythrocytes hyperplasia with eosinophilia were observed in the bone marrow smears, while eosinophilic abscesses and endothelial proliferation could be fo...

I N 1949, Owren first noted a beneficial effect of heparin therapy in autoimmune hemolytic anemia.1 Dramatic therapeutic responses were subsequently reported by other investigators.26 However, neither the value nor the precise mechanism of action of this drug has been elicited in the treatment of autoimmune hemolytic anemia. We have evaluated the use of parenteral heparin in seven patients with...

I T HAS BECOME increasingly apparent that many forms of hemolytic disease are due to hereditary enzyme deficiencies affecting the erythrocytes. The drug-induced hemolytic anemias may be due to glucose-fl-phosphate dehydrogenase (G-6-PD ) deficiency, glutathione reductase (GSSG-R) deficiency, or to a deficiency in reduced glutathione (GSFI ). Nonspherocytic congenital hemolytic anemia may be due...

Gemcitabine is a widely used drug in the treatment of diverse malignancies and its use has been approved by US Food Drug Administration. This associated with rare adverse event, Hemolytic Uremic Syndrome (HUS), characterized acute kidney injury, microangiopathic hemolytic anemia, thrombocytopenia. The purpose this report to draw attention an atypical manifestation severe unusual complication, d...