Polycystic ovary syndrome (PCOS) is a complex disorder with heterogeneity of clinical and endocrine features. Ovarian surgery for ovulation induction has been used in the management of clomiphene citrate-resistant anovulatory women with PCOS. Various types of ovarian surgery have been employed (wedge resection, electrocautery, laser vaporization, multiple ovarian biopsies and others) and all pr...

Menstrual bleeding patterns are considered relevant indicators of reproductive health, though few studies have evaluated patterns among regularly menstruating premenopausal women. The authors evaluated self-reported bleeding patterns, incidence of spotting, and associations with reproductive hormones among 201 women in the BioCycle Study (2005-2007) with 2 consecutive cycles. Bleeding patterns ...

Background: Ovulatory dysfunction accounts for 20-25% of the cases infertility. The main treatment modality anovulatory infertility is ovarian stimulation. Clomiphene citrate (CC) and letrozole (LET) are drugs choice but which best first line debatable. Objective: Compare outcome by CC LET. Method: A prospective randomized controlled trial including two groups subfertile patients was carried ou...

OBJECTIVES Blood flow to uterus and ovaries is demonstrated to be altered during mensturation. Studies has been published stating that blood flow differs also in ovulatory and anovulatory cycles. In this study, using color Doppler ultrasound, we aim to compare uterine, endometrial and ovarian blood flow during ovulatory and anovulatory cycles. MATERIAL AND METHODS Women volunteers who are age...

Abstract Ovulatory disorders are a major factor in female infertility. Our laboratory has identified several populations of cows and population sheep that have excess androgen (High A4) dominant follicles ovarian cortex cultures the US Middle East with increased steroidogenic enzyme production somatic cells. Within our research herd, High A4 females irregular estrous cycles where behavioral est...

PURPOSE To review the clinical and MR imaging findings in adolescents with hemorrhagic pituitary adenomas and to compare those findings with pathologic results and outcome. METHODS We reviewed the clinical records, imaging examinations, surgical and pathologic findings, and follow-up studies in 11 girls and six boys (12 to 20 years old; mean age, 16 years) with pituitary adenomas who were tre...

objective: polycystic ovary syndrome (pcos) is highly associated with anovulatory infertility, features of the metabolic syndrome, including obesity, insulin resistance and dyslipidemia. serum concentrations of high sensitive c- reactive protein (hs-crp) were significantly higher in obese than in non-obese pcos patients at baseline suggesting that the relationship between elevated hs-crp levels...

Ovulation is a precisely timed process by which a mature oocyte is released from an ovarian follicle. This process is initiated by the pituitary surge of luteinizing hormone (LH), is temporally associated with transcriptional regulation of numerous genes, and is presumed to involve the synthesis and/or activation of specific proteases that degrade the follicle wall. The progesterone receptor (P...

OBJECTIVE Dietary phytoestrogens are promoted as alternatives to synthetic estrogens for hormone therapy, however, their effects on the reproductive axis have not been exhaustively studied in vivo. Female aromatase knockout mouse (ArKO) mice are estrogen-free, anovulatory, and have a block in folliculogenesis, hemorrhagic cysts, and development of Sertoli cells within their ovaries. The purpose...

background: in patients with anovulatory infertility the first choice of treatment for ovulation induction is an antiestrogen, most commonly clomiphene citrate (cc). however, 20-25% of the women are resistant to cc and do not ovulate perhaps due to antiestrogenic mechanism of the cc action, which involves long-lasting estrogen receptor (er) depletion. objective: the objective of the study was t...