Cavernous malformations (CMs), characterized by the presence of a hemosiderin rim and intralesional hemorrhage, are relatively common intracranial vascular malformations. Extralesional hemorrhages arising from CMs are seen in a minority of cases, but most of them show typical CM findings on magnetic resonance imaging. Here, the authors report two cases of pathologically confirmed CM presenting ...

A 75-year-old woman with a history of hydroxychloroquinetreated cutaneous lupus erythematosus presented with a bilateral sharply demarcated macular hyperpigmentation on both forearms (Fig. 1) and a partial melanonychia of the right thumb nail. This pigmentation disorder developed gradually over a 6-month period. No retinal pigmentation and no systemic disorder were revealed. Dermoscopy of the n...

The spectrum of lipomatous lesions ranges from benign to highly malignant disease. Differentiation between these mesenchymal is important for pathologist as well clinician indicate prognosis and choose the most appropriate treatment. Hemosiderotic firohistiocytic tumor (HFLT) a rare subtype tumor. diagnosis usually based on clinical, histological, immunohistochemical (IHC) information. We repor...

A man with superficial siderosis showed improvement in symptoms and reduction in hemosiderin by MR imaging following treatment with deferiprone, a lipid-soluble iron chelator.

Lichen aureus is a variant of pigmented purpuric dermatoses. The usual histopathology lichen characterized by subepidermal dense, band-like lymphocytic infiltrate, extravasated erythrocytes, and hemosiderin deposits. We report three patients with on the extremities similar clinical, dermoscopic, histopathological findings dense relatively deep dermal infiltrate accompanied extravasation erythro...

In iron overload, almost all the excess iron is stored intracellularly as rapidly mobilizable ferritin iron and slowly exchangeable hemosiderin iron. Increases in cytosolic iron may produce oxidative damage that ultimately results in cardiomyocyte dysfunction. Because intracellular ferritin iron is evidently in equilibrium with the low-molecular-weight cytosolic iron pool, measurements of ferri...

BACKGROUND Expectant management of serous cystadenoma (SCA) of the pancreas requires an accurate preoperative diagnosis. Previously published cytologic diagnostic sensitivities have ranged widely, from 10% to 100%. In the current study, the authors evaluated the diagnostic sensitivity of endoscopic ultrasound (EUS)-guided fine-needle aspiration biopsy (FNAB) and cross-sectional imaging for SCA....