نتایج جستجو برای: hepatic amyloidosis
تعداد نتایج: 104741 فیلتر نتایج به سال:
BACKGROUND Two kindreds with hereditary systemic amyloidosis caused by the first two mutations to be described in the human lysozyme gene were discovered recently and study of the variant lysozyme has been powerfully informative about mechanisms of amyloid fibrillogenesis. However, the clinical manifestations in these families, additional members of which have lately been identified, have not p...
Prolonged injection of casein results in systemic amyloidosis in mice with impaired hepatic functions due to excessive serum amyloid A (SAA) fibril deposition in liver, spleen, and kidney. We have shown that systemic amyloidosis results in accumulation of SAA fibrils in the brain. The study carried out radiolabeling, Congo red stain, Immuno histochemical studies to source the SAA fibrils that a...
BACKGROUND Systemic amyloidoses is a heterogeneous group of diseases either acquired or hereditary. Amyloidoses can involve the gastrointestinal tract and the nature of the precursor protein that forms the fibrils deposits should be identified to adjust the treatment and evaluate the prognosis. Lysozyme amyloidosis (ALys) is a rare, systemic non neuropathic hereditary amyloidosis with a heterog...
Hepatic disease is usual in large animals. Increases in serum hepatic enzymes and total bile acid concentration may indicate hepatic dysfunction, insult, disease, or failure. While liver disease is particularlyusual in foals, progression to liver failure isn't.Diseases that frequently result in hepatic failure in horses include Theiler's disease, Tyzzer's disease, pyrrolizidine alkaloid toxicos...
Neuropathy is often a major manifestation of systemic amyloidosis. It is most frequently seen in patients with hereditary transthyretin (TTR) amyloidosis, but is also present in 20% of patients with systemic immunoglobulin light chain (primary) amyloidosis. Familial amyloid polyneuropathy (FAP) is the most common form of inherited amyloidotic polyneuropathy, with clinical and electrophysiologic...
BACKGROUND Familial Mediterranean Fever (FMF) is a genetic disease characterized by recurrent febrile attacks and inflammation of serous membranes. Amyloidosis is frequent in untreated FMF patients and is also the most important complication of FMF. It is generally seen with renal, hepatic, gastrointestinal, spleen, testicular and thyroidal involvement. CASE PRESENTATION Herein, we report a c...
Background and Aim: Amyloidosis is a systemic infiltrative disorder characterized by deposition of amyloid fibrils in extracellular spaces. Liver involvement can be seen both primary secondly amyloidosis which subclinical or symptomatic. However, hepatic very rare variant protein primarily occurs liver only. We are presenting an interesting case sub-acute failure due to who underwent living don...
amyloidosis is characterized by an abnormal extracellular deposition of amyloid in different organs, where it usually causes some type of dysfunction. its cause is unknown. five different types of amyloidosis have been described according to the underlying disease; immunoglobulin amyloidosis, familial amyloidosis, senile systemic amyloidosis, secondary amyloidosis and hemodialysis-associated am...
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