Human immune serum globulin (HISG) therapy is the mainstay of treatment for patients with antibody immunodeficiency. Treatment with ‘y-globulin allows many of these patients to remain symptomfree for prolonged periods. Three types of human immunoglobulin are available for therapeutic use: (1) regular HISG for intramuscular (IM) use, derived from a panel of normal donors, therefore containing a ...