E-learning takes advantage of the new features offered by Web services: integration of heterogeneous applications, publicity of available services, etc. As the adoption of this new technology increases it will become necessary to offer intermediary platforms that make it easier to find and locate services, and composing new services from the existing ones. Additionally, it will also be necessar...

This paper considers the Heterogeneous Earliest Finish Time (HEFT) algorithm for scheduling the tasks of an application, represented by a directed acyclic graph, onto a bounded number of heterogeneous machines. We focus on the appropriate selection of the weight for the nodes and edges of the graph, and experiment with a number of different schemes for computing these weights. Our findings indi...

hnRNP K protein, which localizes to the nucleus, cytoplasm and mitochondria, is involved in the various cellular processes that compose gene expression. We used a SAGE-based assay to profile RNAs associated with hnRNP K protein in rat mitochondria. RNA was isolated from mitoplasts obtained from highly purified and RNase-treated mitochondria. Total RNA and RNA associated with hnRNP K protein wer...

Exosomes are released by most cells to the extracellular environment and are involved in cell-to-cell communication. Exosomes contain specific repertoires of mRNAs, microRNAs (miRNAs) and other non-coding RNAs that can be functionally transferred to recipient cells. However, the mechanisms that control the specific loading of RNA species into exosomes remain unknown. Here we describe sequence m...

HnRNP (heterogeneous nuclear ribonucleoprotein) proteins are a large family of RNA-binding proteins that regulate numerous aspects of RNA processing. Interestingly, several paralogous pairs of hnRNPs exist that exhibit similar RNA-binding specificity to one another, yet have non-redundant functional targets in vivo. In this study we systematically investigate the possibility that the paralogs h...

Heterogeneous computing (HC) is the coordinated use of di€erent types of machines, net-works, and interfaces to maximize their combined performance and/or cost-e€ectiveness. HC systems are becoming a plausible technique for eciently solving computationally intensive problems. The applicability and strength of HC systems are derived from their ability to match computing needs to appropriate res...

The grid computing system can support the execution of computationally intensive parallel and distributive applications. The main characteristics of grid computing and heterogeneous computing system are similar. A novel scheduling algorithm, called NHEFT is proposed in this paper to enhance the functions of heterogeneous Earliest-Finish time (HEFT) algorithm. The NHEFT algorithm works for a bou...

NUCLEAR RIBONUCLEAR PROTEINS hnRNP L, hnRNP A1 and hnRNP M Kenneth J. Dery , Shikha Gaur , Marieta Gencheva, Yun Yen, John E. Shively and Rajesh K. Gaur Division of Immunology, Clinical and Molecular Pharmacology Beckman Research Institute of the City of Hope 1450 E. Duarte Road, Duarte, CA 91010 These authors contributed equally to the research Running title: Alternative splicing of CEACAM1 pr...

BACKGROUND Recent studies have shown that heterogeneous nuclear ribonucleoprotein U (hnRNP U), a component of the hnRNP complex, contributes to stabilize the kinetochore-microtubule interaction during mitosis. CENP-W was identified as an inner centromere component that plays crucial roles in the formation of a functional kinetochore complex. RESULTS We report that hnRNP U interacts with CENP-...