نتایج جستجو برای: heterologous expression

تعداد نتایج: 880880  

2015
Stefan M. Gaida Nicholas R. Sandoval Sergios A. Nicolaou Yili Chen Keerthi P. Venkataramanan Eleftherios T. Papoutsakis

A key limitation in using heterologous genomic or metagenomic libraries in functional genomics and genome engineering is the low expression of heterologous genes in screening hosts, such as Escherichia coli. To overcome this limitation, here we generate E. coli strains capable of recognizing heterologous promoters by expressing heterologous sigma factors. Among seven sigma factors tested, RpoD ...

2017
Jeroen S Dickschat Jan Rinkel Patrick Rabe Arman Beyraghdar Kashkooli Harro J Bouwmeester

The product obtained in vitro from a diterpene synthase encoded in the genome of the bacterium Chitinophaga pinensis, an enzyme previously reported to have germacrene A synthase activity during heterologous expression in Escherichia coli, was identified by extensive NMR-spectroscopic methods as 18-hydroxydolabella-3,7-diene. The absolute configuration of this diterpene alcohol and the stereoche...

Journal: :Current opinion in biotechnology 1999
T A Kost J P Condreay

Baculovirus expression vectors are widely used for expressing heterologous proteins in cultured insect cells. Recent advances include further development of the system for production of multi-subunit protein complexes, co-expression of protein-modifying enzymes to improve heterologous protein production, and additional applications of baculovirus display technology. The application of modified ...

Journal: :The Scientific Notes of the I. P. Pavlov St. Petersburg State Medical University 2013

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