The management of heterotopic ossification is controversial. This is a rare case affecting both hips and knees of a 22-year-old woman that prevented her from walking. The management and the outcome, three years after excision of the ossific masses, as well as the measures to prevent recurrence after excision of the heterotopic ossification, are discussed.

We examined whether a selective cyclooxygenase-2 (COX-2) inhibitor (celecoxib) was as effective as a non-selective inhibitor (ibuprofen) for the prevention of heterotopic ossification following total hip replacement. A total of 250 patients were randomised to receive celecoxib (200 mg b/d) or ibuprofen (400 mg t.d.s) for ten days after surgery. Anteroposterior radiographs of the pelvis were exa...

Heterotopic ossification is a complicated and significant medical problem characterized by abnormal growth of bone in soft tissues. It occurs most commonly around a joint following surgery or trauma and is one of only a few benign conditions commonly treated with radiation therapy. In its severe form, the condition causes pain, loss of function, and restricted range of motion in the affected jo...

Heterotopic ossification in colorectal carcinoma is extremely rare. This report presents the case of a 57-year-old male who had undergone a low anterior resection following a diagnosis of rectal carcinoma. Histological examination showed heterotopic ossification in the tumor. The patient was referred to Ibaraki Medical Center, Tokyo Medical University, with a diagnosis of rectal carcinoma by a ...

OBJECTIVES Heterotopic ossification which may develop following elbow injuries or elbow surgery may result in complete loss of elbow functions. We evaluated the results of surgical treatment for ankylosis of the elbow due to posttraumatic heterotopic ossification. METHODS The study included seven patients (6 males, 1 female; mean age 36 years; range 23 to 55 years) who developed heterotopic o...

©2004 British Editorial Society of Bone and Joint Surgery doi:10.1302/0301-620X.86B6. 15356 $2.00 J Bone Joint Surg [Br] 2004;86-B:783-7. Heterotopic ossification can be defined as the formation of bone in tissues which normally exhibit no properties of ossification. It is characterised by the rapid development of calcified bone in soft tissues. Ectopic bone can develop from immature osteoid in...

A case of heterotopic ossification developed after traumatic laceration of the middle finger. It is extremely rare for heterotopic ossification to locate in the finger. The diagnosis was accomplished with plain radiographs as well as with MRI and confirmatory study with histopathological microscopic examination which demonstrated nubbin of bone surrounded by fibrovascular connective tissue, and...

Intra-abdominal heterotopic ossification is extremely rare with only approximately 30 cases having been reported. While most reported cases have involved the mesentery, ossification of the peritoneum is even rarer. The pathogenesis remains undetermined but is generally considered a reactive process in response to various stimuli. Histologically, it is composed of a peripheral area with bone for...

Heterotopic bone formation is a very rare event in the gastrointestinal tract including in the appendix. Here we report three cases of heterotopic ossification in appendiceal mucinous neoplasms, one occurring in an appendiceal mucinous cystadenoma, another in a low-grade appendiceal mucinous neoplasm, and the third occurring in an appendiceal mucinous adenocarcinoma. The clinicopathologic chara...