Type-B T cells raised against the immunodominant peptide in hen egg lysozyme (HEL(48-62)) do not respond to whole lysozyme, and this has been thought to indicate that peptide can bind to l-A(k) in different conformations. Here we demonstrate that such T cells recognize a deamidated form of the HEL peptide and not the native peptide. The sequence of the HEL epitope facilitates rapid and spontane...

The general concept of exchangeability allows the more flexible modelling of most experimental setups. The representation theorems for exchangeable sequences of random variables establish that any coherent analysis of the information thus modelled requires the specification of a joint probability distribution on all the parameters involved, hence forcing a Bayesian approach. The concept of part...

We present a general and simple procedure to construct quasi-interpolants in hierarchical spaces, which are composed of a hierarchy of nested spaces. The hierarchical quasi-interpolants are described in terms of the truncated hierarchical basis. Once for each level in the hierarchy a quasi-interpolant is selected in the corresponding space, the hierarchical quasi-interpolants are obtained witho...

The hierarchical reconstruction (HR) [9, 20] is applied to a piecewise quadratic spectral volume method on two-dimensional unstructured grids as a limiting procedure to prevent spurious oscillations in numerical solutions. The key features of this HR are that the reconstruction on each control volume only uses adjacent control volumes, which forms a compact stencil set, and there is no truncati...

A stabilization problem for a general nonlinear control system is considered. In particular the control corresponding to the equilibrium position may belong to the boundary of the control set. A linear control system is considered as a first approximation for the original problem. The right-hand side of the linear system generates a set-valued map of a special type known as a convex process. Th...