نتایج جستجو برای: high affinity receptor

تعداد نتایج: 2600326  

Journal: :Proceedings of the National Academy of Sciences 2009

Journal: :The Journal of pharmacology and experimental therapeutics 1997
B L Roth M S Choudhary N Khan A Z Uluer

In this study, the relationship between high-affinity agonist binding and second messenger production was examined at native and mutant 5-hydroxytryptamine2A receptors. At native 5-hydroxytryptamine2A receptors all agonists, with the exception of quipazine, discriminated between high- and low-affinity states of the receptor, as determined by analysis of competition binding assays. There was no ...

Journal: :The Journal of Experimental Medicine 1990
M A Caligiuri A Zmuidzinas T J Manley H Levine K A Smith J Ritz

In this study, we have used radiolabeled IL-2 binding assays, Northern blot analysis, immunofluorescent flow cytometry and cell sorting, as well as proliferation and cytotoxicity assays to perform an extensive phenotypic and functional characterization of the IL-2 receptor in normal resting human peripheral blood lymphocytes. Our results indicate that almost all T cells (greater than 98%) expre...

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