This article describes a simple and fast high-performance liquid chromatography method for the determination of methotrexate (MTX) in plasma. Samples were collocted from children receiving high-dose MTX at shafa Hospital (Ahvaz University of Medical sciences, Ahvaz, iran) at various times after the end of eachinfusion. Plasma was deproteinized with trichloroacetic acid and the supernatant was i...

This article describes a simple and fast high-performance liquid chromatography method for the determination of methotrexate (MTX) in plasma. Samples were collocted from children receiving high-dose MTX at shafa Hospital (Ahvaz University of Medical sciences, Ahvaz, iran) at various times after the end of eachinfusion. Plasma was deproteinized with trichloroacetic acid and the supernatant was i...

       An accurate and sensitive reversed-phase high-performance liquid chromatograph-ic method for determination of sertraline in human serum is described using 4-chloro-7-nitrobenzofurazan as pre-column derivatization agent. The drug and an internal standard (azithrimycin) were extracted from serum using a mixture of diethyl ether-chloroform and subjected to the pre-column derivatization with...

background ziziphora tenuior l. known as kakuti in persian, is used in traditional medicine for fever, dysentery, uterus infection and as an analgesic. it is used also in the treatment of gastrointestinal disorders as carminative, or remedy of diarrhea or nausea. major components of plant essential oil including pulegone, isomenthone, thymol, menthone, and piperitone are suggested to be respons...

background valproic acid is widely used as an anticonvulsant and mood-stabilizing drug in the treatment of epilepsy. determination of serum valproic acid is required in epilepsy therapy for efficient control of seizures. objectives in the present study, the gas chromatography method was applied to determine serum valproic acid and resulting data were compared with those obtained by high perform...

A h igh-per formance l i q u i d chromatography (HPLC) method has been deve loped f o r t h e s e p a r a t i o n of o l e f i n , s a t u r a t e , and a r o m a t i c hydrocarbons found i n h i g h b o i l i n g d i s t i l l a t e s and r e s i d u e s of s h a l e o i l and i n whole s h a l e o i l s . The dual-column chromatographic system uses s i l i c a g e l i n one column and s i l i...

BACKGROUND Determining folate intake is difficult because existing folate data in food-composition tables are scarce and unreliable. OBJECTIVE The purposes of this study were first to analyze 125 of the most important foods that contribute to folate intake in the Netherlands and second to estimate the folate intake of a representative sample of the population. DESIGN We analyzed the folate ...