نتایج جستجو برای: high shear granulation
تعداد نتایج: 2121017 فیلتر نتایج به سال:
The digitization of manufacturing processes has led to an increase in the availability process data, which enabled use data-driven models predict outcomes these processes. Data-driven are instantaneous simulate and can provide real-time predictions but lack any governing physics within their framework. When data deviates from original conditions, may not agree with physical boundaries. In such ...
This article summarizes the investigation of in-line particle characterization during high shear wet granulation (HSWG) using focused beam reflectance measurement (FBRM) for enhanced process understanding, which is part of an effort to develop this drug product within the framework of quality by design (QbD) and process analytical technology (PAT). Traditionally, the effectiveness of in-line mo...
Strong velocity gradients at granular borders appear to be the source of unresolved velocity fluctuations detectable as line broadening variations of magnetically and thermally insensitive absorption lines. Based on spectrograms of high spatial and spectral resolution taken with the German Vacuum Tower Telescope (VTT) in Izaña (Tenerife) we study the strong velocity gradients and the unresolved...
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