Sclerosing Polycystic Adenosis (SPA) is a rare disease of the salivary glands, first described by Smith et al. in 1996, with histomorphological aspects similar to those from breast fibrocystic disorders1. Its pathogenesis is still unclear; however, it is considered a pseudo-neoplastic or reactive process. Recently, Skálová et al. showed clonality in six SPA cases. SPA affects mainly the parotid...

Gain-of-function mutations in leucine-rich kinase 2 (LRRK2) are associated with increased incidence of Parkinson disease (PD); thus, pharmacological inhibition LRRK2 activity is postulated as a disease-modifying treatment PD. Histomorphological changes lungs nonhuman primates (NHPs) treated small-molecule inhibitors have brought the safety this approach into question. Although it remains unclea...

Background: Progesterone is used in combined oral contraceptive pills and also has its effect on the respective receptors which are responsible for sexual development. Bronchial asthma emerges to be a major health issue Pakistan with estimated prevalence about 5% of total population. Epidemiological studies highlight that one considerable risk factor morbidity mortality inflammatory lung diseas...

Conducting routine allergy tests of cattle with a simultaneous sample in TB-prone farms is necessary to confirm the stage epizootic process. The purpose research – explore pathomorphological changes cows upon detection para allergic reactions during diagnostic testing for tuberculosis. diagnosis tuberculosis animals was performed comprehensively using all methods control provided guidelines epi...

Background: Spleen and liver is secondary lymphoid organ that highly sensitive to different chemicals. Widespread use of pesticides in agriculture has always been a matter concern. And surprisingly, atrazine distinguishes out for being used more frequently among numerous harmful pesticides. As result, long term exposure other thought produce metabolic abnormalities; however, little known about ...

BACKGROUND Proper histomorphological interpretation of intestinal acute graft versus host disease (A-GVHD) associated with allogeneic bone marrow transplantation (BMT) is critical for clinical management. However, studies methodically evaluating different histomorphological features of A-GVHD are rare. METHODS Colonic biopsies from 44 allogeneic BMT patients having biopsy-proven cutaneous A-G...

AIM Investigation has been carried out to validate folkloric claim of the potential of Ipomoea digitata (ID) based on reproductive health status in experimentally induced male albino rats. MATERIALS AND METHODS Emulsified neem oil fed albino rats were orally administered root powder of ID suspended in water for the doses of 250 and 500 mg/kg body weight for 40 days. Change in organ weight, sp...

The importance of canine reproduction is steadily increasing and little is known about the canine cervix and ovary so far. The aim of this study is to describe the histomorphology of the canine cervix, ovary and to determine its correlation with the stage of oestrous cycle and to circulating concentrations of progesterone (P4) and estradiol17beta (E2) and vaginal cytology respectively. Twenty h...