Toxic multinodular goiter is a cause of nonautoimmune hyperthyroidism and is believed to differ in its nature and pathogenesis from toxic adenoma. Gain-of-function mutations of the TSH receptor gene have been identified as a cause of toxic adenoma. The pathogenesis at the molecular level of hyperfunctioning nodules in toxic multinodular goiter has yet not been reported. Six patients with a sing...

in order to study the effect of pyridate, bentazon and imazethapyr herbicides on chickpea growth, nodulation and biological nitrogen fixation, a greenhouse experiment was conducted at ferdowsi university of mashhad in 2010. experimental type was completely randomized design with four replications. treatments included pyridate, bentazon and imazethapyr herbicides application in 1200, 720 and 75 ...

Thyroid nodules are common, occurring in almost two-thirds of some populations; among these only about 7% are malignant. The most important question with any new discovered thyroid nodule is, “is this malignant?” The main arbiter of malignancy or benignity remains fine needle aspiration and the mainstay of treatment surgery. But given the resources involved, doing an FNAC or surgery in every di...

The endometrial stromal nodule is a benign tumor composed of differentiated endometrial stromal cells arranged as a well circumscribed nodule with smooth non-invasive margins. They are rare neoplasms, diagnosed in most instances by microscopy. Although nodules are benign in nature, hysterectomy is the treatment of choice to enable evaluation of the tumor margins which are well demarcated in...

sister mary joseph nodule or sister mary joseph sign refers to a palpable nodule bulging into the umbilicus as a result of metastasis of a malignant cancer in the pelvis or abdomen. a rare case of sister mary joseph nodule, manifesting as ascites, cachexia and bleeding per rectum, is presented without any primary tumor despite extensive search for the same. normal 0 false false false microsofti...

to evaluate symbiotic effectiveness and salt tolerance of sinorhizobium meliloti strains, 50 rhizobial strains were isolated from root nodules of medicago sativa cultivated in tehran and zanjan fields. under n-free conditions, the symbiotic effectiveness of different sinorhizobium meliloti strains of bami cultivar were evaluated under greenhouse conditions using 50 sinorhizobium meliloti strain...

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conclusions if the indications and contraindications of minimally invasive thyroidectomy are taken into account, it seems to be a safe procedure and regarding the benefits of this procedure, it's recommended that surgeons pay more attention to this newly developed technique. introduction since 1996 with improvement of endoscopic instrumentation several novel minimally invasive techniques have b...

Background: Fine needle aspiration biopsy (FNAB) is usually used to distinguish the malignant and benign nodules. Applying a biopsy needle evokes a sense of fear and pain in the patients. Although some studies refute the usefulness of local anesthesia (LA) prior to fine needle aspiration biopsy, it is still debatable. This prospective cross-sectional study intended to evaluate the effect of LA ...