A novel bioresponsive controlled-release biosensor using Au nanocages capped with an aptamer-based molecular gate was reported for the first time. The use of aptamers as caps has proven to be a suitable method for the preparation of "bio-gated" delivery systems that can be selectively opened in the presence of target biomolecules.

Patch tests were introduced as a diagnostic tool in the late nineteenth century. Since then, they have improved considerably becoming what they are today. Patch tests are used in the diagnostic investigation of contact dermatitis worldwide. Batteries or series previously studied and standardized should be used in patch testing. The methodology is simple, but it requires adequate training for th...