Cervical squamous intraepithelial lesions (SIL) and cervical cancer (CxCa) develop because of high-risk human papillomavirus (HR-HPV) infection; however, other cofactors such as endogenous hormones could contribute to the development this neoplasia.

Relevance: Human papillomavirus (HPV) is the most common sexually transmitted virus in active men and women. The direct
 proven relationship between HPV infection cervical cancer development global epidemiological studies to ensure prevention
 areas with high prevalence.
 study aimed analyze age-related prevalence over past decade.
 Methods: Sources for literature review wer...

High risk Human Papilloma Virus (HR-HPV) DNA integration into the human genome is one of the key stages in the progression of cervical neoplasia. This mini-review highlights the importance of HPV integration as a potential biomarker for cervical screening and briefly describes the main methods used to detect HPV integration: Amplification of Papillomavirus Oncogene Transcripts (APOT), Restricti...

We report here identification and validation of the first papillomavirus encoded microRNAs expressed in human cervical lesions and cell lines. We established small RNA libraries from ten human papillomavirus associated cervical lesions including cancer and two human papillomavirus harboring cell lines. These libraries were sequenced using SOLiD 4 technology. We used the sequencing data to predi...

HPV: Human papillomavirus INTRODUCTION Common cutaneous warts caused by human papillomavirus (HPV) strains 1, 2, and 4, can be challenging to treat. Immunosuppressed patients are especially vulnerable to this infection, and the warts may cause physical and psychologic distress. There are currently 3 commercially available vaccines in the United States that target HPV strains commonly associated...

Background: Breast cancer is the malignancy in humans and other mammals. Several risk factors are involved in their appearance such as higher hormone levels and obesity. Identification of a mouse mammary tumor virus supports a viral etiology for breast tumors in animals. Viruses have been implicated in the development of various cancers, but viral induction for formation breast cancer is contro...

Human papillomavirus (HPV) infection is a leading cause of morbidity and mortality in women worldwide. The virus associated with benign warts broad spectrum malignancies, including cervical cancer, considered disease high clinical relevance, especially developing countries. In this study we developed the production recombinant proteins HPV16 L1 L2 human cells suspension (293-F), which were tran...

Human papillomavirus (HPV) infection is a necessary factor in the development of cervical cancer. A new HPV screening method, "Human Papillomavirus Genotyping (HPG)", was developed to detect 29 HPV genotypes distribution in China. The utility of HPG was compared to Hybrid Capture 2 High-Risk HPV DNA test (HC2), and it was determined that the HPG test had been proven to be a more credible and se...

background and objective: human papillomavirus (hpv) is one of the possible etiologic factors  in development of esophageal squamous cell carcinoma (escc). in this study we aimed to study the  role of hpv in escc. patients and methods:in this study, 140 cases of escc were analyzed for the hpv dna by  polymerase chain reaction (pcr) using gp5+/gp6+ primers for l1 open reading frame (orf) to  am...

Oropharyngeal squamous cell carcinoma (OPSCC) has historically been attributable to tobacco and alcohol exposure saw a decline in incidence after societal norms shifted away from smoking. In recent decades, this disease had re-emergence due human papillomavirus (HPV) infection, now surpassing cervical cancer as the number 1 cause of HPV-related United States. HPV-positive OPSCC differs HPV-nega...