نتایج جستجو برای: hydatidiform mole
تعداد نتایج: 22553 فیلتر نتایج به سال:
Hydatidiform mole is an abnormal human pregnancy characterized by the fetus being absent or nonviable, and the chorionic villi being vesicular and with trophoblastic hyperplasia. Most often, the mole phenotype is seen in conceptuses with an excess of paternally inherited genome set(s) relative to maternally inherited genome set(s), suggesting that the phenotype is caused by an excess of genome ...
The methylation status of genes in hydatidiform mole and choriocarcinoma and its significance is relatively unexplored. We investigated the methylation status of the promoter regions of six genes, p16, HIC-1, TIMP3, GSTP1, death-associated protein kinase (DAPK), and E-cadherin in 54 hydatidiform moles, five choriocarcinomas, and 10 first trimester placenta by methylation-specific polymerase cha...
A complete hydatidiform mole (CHM) is a conceptus with only sperm-derived chromosomes. Here, we report on CHM genomic DNA identical to that of the paternal somatic cells. The developed in woman who had undergone intrauterine implantation blastocyst obtained through vitro injection presumed round spermatid into one her oocytes. was genetically peripheral white cells husband and contained no mate...
OBJECTIVE To study the potential of long interspersed element-1 (LINE-1) methylation change in the prediction of postmolar gestational trophoblastic neoplasia (GTN). METHODS The LINE-1 methylation pattern from first trimester placenta, hydatidiform mole, and malignant trophoblast specimens were compared. Then, hydatidiform mole patients from 11999 to 2010 were classified into the following 2 ...
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