BACKGROUND Some studies in the literature support the use of either inhaled or systemic steroids for the treatment of chemical pneumonitis; however, no data have been published on the combined use of inhaled and intravenous (IV) steroids. OBJECTIVES This brief report describes the effective use of inhaled plus systemic steroids in managing six critical pediatric patients. PATIENTS AND METHO...

This article focuses on issues of safety and monitoring when immunosuppressive pharmacologic therapies are prescribed for the treatment of connective tissue disease (CTD)-associated interstitial pneumonias, vasculitides, and bronchiolitis. Prospective, randomized placebo-controlled clinical trials have yet to be performed to evaluate the efficacy and safety of various immunosuppressive agents u...

OBJECTIVES/HYPOTHESIS We describe management of an infant with chronic aspiration as a result of severe and rarely described laryngeal dysgenesis. RESULTS A neonate with severe maldevelopment of the laryngeal structures required tracheostomy for respiratory distress on day-of-life 1, but the patient continued to have aspiration pneumonias. After failing to improve with conservative measures, ...

TOPIC: Pulmonary Manifestations of Systemic Disease TYPE: Medical Student/Resident Case Reports INTRODUCTION: Granulomatosis with polyangiitis (GPA) is a necrotizing small vessel vasculitis classically involving the upper and lower respiratory tract kidneys. We present patient GPA which initially presented as "recurrent pneumonias" unresponsive to antibiotics ultimately culminating in presentat...