The hypothesis tested is that a 24-h pre-irradiation-exposure of peripheral blood lymphocytes (PBL) to the benzene metabolite hydroquinone (HQ), at doses that are non-acutely toxic (5 microM), induces a less efficient G2-M-checkpoint and enhances the G2-chromosomal radiosensitivity in a statistically significant manner (p<0.01). A less efficient G2-M-checkpoint may allow the transition of damag...

To improve the hydroquinone (HQ) determination limit in wastewater and contribute to the comprehensive utilization of lignin, a zinc oxide-loaded lignin-based carbon fiber (ZCF) was prepared by a combination of electrospinning and thermal treatment processes, and was applied in electrocatalytic oxidation of HQ using cyclic voltammetry (CV). The characterization of composites was conducted by X-...

Hydroquinone (HQ) has been reported to produce chromosomal effects in some in vivo and in vitro animal models. Its potential for inducing similar effects in human lymphocytes is less clear. The purpose of this study was to examine human lymphocytes treated with HQ for the presence of chromosomal anomalies, using an accepted assay for micronuclei. In addition, the stability of HQ in culture medi...

Capacitive deionization (CDI) has newly emerged as a desalination technology because of its energy and cost effectiveness. In particular, CDI using flow electrode (FCDI) significantly increased salt removal by continuous even at concentrations both brackish seawater. Since mainly uses the electrosorption ions onto an electric double layer on electrodes, carbon materials their derivatives have b...

Rheumatoid arthritis (RA) development is strongly associated with cigarette smoke exposure, which activates the aryl hydrocarbon receptor (AhR) as a trigger for Th17 inflammatory pathways. We previously demonstrated that exposure to hydroquinone (HQ), one of major compounds tar, aggravates symptomatology in rats. However, mechanisms related HQ-related RA still remain elusive. Cell viability, cy...

Cytochrome P450 (CYP) 2E1 was the most efficient CYP enzyme that oxidized benzene to soluble and covalently bound metabolites in rat and human liver microsomes. The covalent binding was due mostly to the formation of benzoquinone (BQ), the oxidation product of hydroquinone (HQ), and was inversely related to the formation of soluble metabolites. In rats, inhalation of benzene (4 mg/liter of air)...

The impregnation of size-controlled gold nanoparticles (AuNPs) on an anatase TiO2 structure ([email protected]2) was studied for the photoelectrochemical detection hydroquinone (HQ) under visible light illumination integrated into a flow injection analysis (FIA) setup. crystalline form preserved during synthesis and homogeneous distribution AuNPs over confirmed. Its photoelectrocatalytic activi...

Graphene aerogel materials have attracted increasing attention owing to their large specific surface area, high conductivity and electronic interactions. Here, we report for the first time a novel strategy for the synthesis of nitrogen-doped activated graphene aerogel/gold nanoparticles (N-doped AGA/GNs). First, the mixture of graphite oxide, 2,4,6-trihydroxybenzaldehyde, urea and potassium hyd...

AIMS Statins, inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase, possess pleiotropic effects that have been extended to modulation of various cellular behaviors. This study aimed to examine whether statins modulate vascular endothelial growth factor A (VEGF-A) expression in human retinal pigment epithelium (RPE) cells. MAIN METHODS Human RPE cells (h1RPE7), damaged by hydroquinone...

We investigated the ability of an acute pro-oxidant challenge in vivo to deteriorate glycaemic control and insulin action in the obese Zucker rat, a model of insulin resistance associated with oxidant stress. In obese animals, the daily administration for 1 week of hydroquinone (HQ) in combination with L-buthionine sulphoximine (BSO), elevated fasting plasma glycaemia and insulinaemia and marke...