These analyses show that this cyclic A M P phosphodiesterase.contains at least 15ng of zinc per activity unit. The sodium dodecyl sulphate/polyacrylamide-gel electrophoresis of fraction 18 suggests that the specific activity of pure enzyme is at least 104 units/mg, and the results of Fujimoto et al . (1974), obtained at 37"C, suggest it may be as high as 160 units/mg at 30°C. Thus 1 mol (65000g...

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The localized corrosion behavior of a galvanic aluminum copper couple was investigated by in situ fluorescence imaging with a fiber-optic imaging sensor. Three different, but complementary methods were used for visualizing remote corrosion sites, mapping the topography of the metal surface, and measuring local chemical concentrations of H+, OH-, and Al3+. The first method is based on a pH-sensi...

A Pseudomonas sp. isolated from sewage by enrichment culture on quinoline metabolized this substrate by a novel pathway involving 8-hydroxycoumarin. During early growth of the organism on quinoline, 2-hydroxyquinoline accumulated as the intermediate; 8-hydroxycoumarin accumulated as the major metabolite on further incubation. 2,8-Dihydroxyquinoline and 2,3-dihydroxyphenylpropionic acid were ide...

The possibility of imparting an antibacterial effect to cellulose tissue dyed with the product azo coupling diazotized 4,4’-diaminostilbene-2,2’-disulfonic acid 8-hydroxyquinoline has been shown. It was found that fabrics by fixing dye a silver salt have significant effect, which lasts at least 10 washings.

This investigation was carried out to develop a convenient alternative method for examining the performance and determining the dead time of a stopped-flow fluorometer. We examined the kinetics for the formation of the fluorescent Mg2+-8-hydroxyquinoline chelate in aqueous solutions. The reversible association of the Mg2+ ion with 8-hydroxyquinoline is a second-order process whose on and off ra...

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In this communication, we present the synthesis of new platinum complexes based on hydroxyquinoline ligands. We demonstrate the importance and the role of the halogen substitution as well as the chelation, which are essential structural characteristics for finding good cytotoxicities.