Hypochlorous acid (HOCl), an oxidant produced by myeloperoxidase (MPO), induces protein and lipid oxidation, which is implicated in the pathogenesis of atherosclerosis. Individuals with mildly elevated bilirubin concentrations (i.e., Gilbert syndrome; GS) are protected from atherosclerosis, cardiovascular disease, and related mortality. We aimed to investigate whether exogenous/endogenous uncon...

A number of genetic risk factors have been implicated in the development of neonatal severe hyperbilirubinaemia. This includes mutations in the uridine glucoronosyl transferase 1A1 (UGT1A1) gene which is responsible for unconjugated hyperbilirubinemia in Gilbert's Syndrome. We studied the prevalence of UGT1A1 gene mutations in a group of Malay neonates to determine whether they are risk factors...

conclusions it is important to consider tb meningitis in newborns with perinatal ivh and concomitant hydrocephalus particularly when the mother has a history of tb prior to or during pregnancy. introduction congenital tuberculosis is an infrequently encountered condition and only 300 cases were reported in the literature till 1989. there are no specific signs and symptoms pathognomonic for cong...

the aim is the study on the impact of pethedine 4 hours before labor on newborn. data was gathered based on the apgar scores in first and fifth minutes after birth. three groups of mothers were selected: without any use of pethedine, use of pethedine less than 4 hours before labor and use of pethedine more than 4 hours before labor. the data was analyzed by using computer programs. there was no...

background: various strategies have been suggested for the treatment of respiratory distress syndrome (rds). objectives: the aim of this study was to compare the efficacies of two common methods of rds management among neonates with low birth weight. patients and methods: a cohort study was conducted on 98 neonates with definite diagnosis of rds during 2008-2009. the neonates were divided into ...

kangaroo mother care (kmc) is effective care method that avoids aggressive routinely methods in neonatal wards. objective of this study was comparing kmc with conventional care (incubator) of premature infant in neonatal ward. this study was a randomized controlled clinical trial that has been done in 17 months. 40 premature neonates whose birth weight was less than 1500gr were enrolled in the ...

background: rabies is a fatal infectious disease and rabies post-exposure prophylaxis is the method of choice for prevention of human rabies. case series: we report rabies antibody levels in cord blood and also in serum of pregnant women who were bitten by suspected animals to rabies and were immunized by purified vero cell rabies vaccine (pvrv) and human rabies immunoglobulin (hrig) serum. dur...

background: this study was performed to find out whether transcutaneous bilirubinometry could be a valid screening method for hyperbilirubinemia in preterm infants, especially for those who needed mechanical ventilation. methods: we evaluated 63 preterm iranian newborns who were managed in the neonatal intensive care unit of shahidbeheshti university hospital, isfahan, iran from april 2009 to a...