In lung cancer patients, hypercalcemia is a fairly common metabolic problem associated with malignancy. However, the occurrence of hypercalcemia in lung cancer patients means an ominous prognostic sign. As hypercalcemia often causes early death, quick diagnosis and treatment for hypercalcemia are required. A 69-year-old woman was admitted to our hospital with anorexia caused by hypercalcemia. O...

Hypercalcemia is found frequently in patients with cancer. Besides the etiology related to the malignancy, other causes should be considered in the differential diagnostic, as primary hyperparathyroidism, granulomatous diseases and the use of thiazide diuretics. We present a case report of a severe hypercalcemia due to a rare association and review the relevant literature. A female patient, 57 ...

Purpose Hypercalcemia is an electrolyte disorder found in cancer patients which can complicate the disease and hasten death. It is classified by a blood serum calcium level of 2.6 mmol/l and above and its incidence is related to malignancy type. The object of this study is to explore the distribution of hypercalcemia amongst different cancer forms and to record the effects on mortality. The stu...

Abstract Background A rare cause of primary hyperparathyroidism (PHPT) is a parathyroid carcinoma. Hypercalcemia with an elevated hormone (PTH) level seen in recurrent and metastasis disease cases often refractory to medical therapy, thus surgical resection recommended when possible. We performed debulking surgery for pleural dissemination cancer improvement symptoms patient hypercalcemia. Case...

OBJECTIVE Our objective was to determine the causes and relative prevalence of hypercalcemia in patients at a major community hospital in Okinawa, Japan. Additionally, we compared these causes of hypercalcemia with the previously published international data. MATERIALS AND METHODS We analyzed all patients with hypercalcemia in a community teaching hospital in Okinawa, Japan, from 1999 to 2002...

Hypercalcemia secondary to malignancy is rare in children and the majority is caused by tumor-produced parathyroid hormone-related protein (PTHrP). We report a case of hypercalcemia refractory to bisphosphonate and corticosteroid therapy, but responsive to denosumab. A 17-year-old boy with epidermolysis bullosa (EB) and advanced squamous cell carcinoma (SCC) of the left leg was referred with se...

Hypercalcemia in children is a rare metabolic finding. The clinical picture is usually non-specific, and the etiology includes several entities (metabolic, nutritional, drug-induced, inflammatory, cancer-associated, or genetic) depending on the age at presentation, but severe hypercalcemia is associated mainly with malignancy in childhood and sepsis in neonates. Severe parathyroid hormone (PTH)...

conclusions io-pth levels should become normal or to drop by at least 80% during successful parathyroidectomy. persistent elevations of io-pth after resection of an abnormal gland dictate the need for bilateral exploration. background we hypothesized that io-pth levels would decline to normal or near normal after successful parathyroidectomy. objectives evaluate efficacy and predictive factor o...

Tuberculosis is a serious public health issue in developing countries. Hypercalcemia, though reported granulomatous disease, mild and asymptomatic tuberculosis. A 16 year old girl female presented with significant weight loss, loss of appetite on examination hepatosplenomegaly. Ultrasound abdomen (USG) showed mesenteric retroperitoneal lymphadenopathy hepatosplenomegaly ascites. We report an un...

Hypercalcemia is a frequent complication of multiple myeloma and has been observed in 43% of the 76 patients admitted to the Clinical Center of the National Institutes of Health from 1953 to 1961 (2). The pathogenesis of the hypercalcemia associated with multiple myeloma has been attributed to excessive bone resorption (3). Carbohydrate-active steroids have been successfully used to correct hyp...