Hyperlipidemia is considered to be a high lipid level in blood, can induce metabolic disorders and dysfunctions of the body, and results in some severe complications. Therefore, hunting for some metabolite markers and clarifying the metabolic pathways in vivo will be an important strategy in the treatment and prevention of hyperlipidemia. In this study, a rat model of hyperlipidemia was constru...

OBJECTIVES To determine the various etiologies of primary and secondary hyperlipidemia among children visiting the pediatric endocrine clinic. Methods: This is a retrospective, cross-sectional, cohort study conducted at King Abdulaziz University Hospital (KAUH), Jeddah, Kingdom of Saudi Arabia from January 2010 to 2015 that included 253 children aged from birth to 12 years old. Data were obtain...

Introduction: Diabetes and hyperlipidemia are two major factors involved in cardiovascular disease. The medical treatment and reduction of the effects of these conditions are key modalities in the prevention of heart disease. The term diabetic dyslipidemia supports the hypothesis that insulin resistance is a potential cause of dyslipidemia. This research study is one of the few that attempts to...

BACKGROUND- Individuals living in primary care health professional shortage areas (PC-HPSA), often have difficulty obtaining medical care; however, no previous studies have examined association of pc-hpsa residence with prevalence of cardiovascular disease risk factors. METHODS AND RESULTS- To examine this question, the authors used data from the Multi-Ethnic Study of Atherosclerosis baseline e...

objective(s):in this study, we aimed at evaluation of electrophysiological and histopathalogical characteristics of statin-induced muscle injury as well as clinical features of patients who develop this condition in terms of frequency and pattern of evolution. materials and methods: forty patients (age 39-74 years) including 25 subjects with type 2 diabetes mellitus, 9 with cardiovascular disea...

OBJECTIVE To examine dose-response relationships between the cumulative number of months women lactated and postmenopausal risk factors for cardiovascular disease. METHODS We examined data from 139,681 postmenopausal women (median age 63 years) who reported at least one live birth on enrolling in the Women's Health Initiative observational study or controlled trials. Multivariable models were...

BACKGROUND AND PURPOSE Stroke prevention clinics (SPCs) are not usually involved with the active management of hypertension, hyperlipidemia, diabetes, and smoking. The effect of consultations generated at SPCs on the adequacy of the management of these risk factors for stroke has not been well described, and few studies have long-term follow-up. METHODS We performed a prospective study of 119...

OBJECTIVES To explore the influence of comorbidities on clinical outcomes and disease activity in rheumatoid arthritis (RA). METHODS In patients included in the cross-sectional observational multicenter international study COMORA, demographics, disease characteristics and comorbidities (hypertension, diabetes, hyperlipidemia, renal failure, ischemic heart disease, stroke, cancer, gastro-intes...

Diabetes mellitus (DM) is known as metabolic disorders showing hyperglycemia and hyperlipidemia due to the dysfunction of pancreatic islets [1]. The prevalence of DM in clinics is markedly increased and it will reach approximately 439 million in 2030 [2]. Generally, DM is mentioned to include two main subtypes, Type 1 (Insulin dependent diabetes) and Type 2 (Non-insulin dependent diabetes) subt...