Hypertensive disorders of pregnancy affect up to 15% of pregnancies and the most severe form, pre-eclampsia, is the leading cause of maternal death in the UK today. Pre-eclampsia is a multisystem disorder affecting virtually every organ and system in the body, with hypertension and proteinuria, the traditional diagnostic features, representing two facets of a complex pathophysiological process....

BACKGROUND Hypertensive disorders of pregnancy are the most common causes of adverse maternal & perinatal outcomes. Such investigations in resource limited settings would help to have great design strategies in preventing maternal and perinatal morbidity and mortality. AIM To determine management outcome and factor associated with pregnancy related hypertensive disorder in Mettu Karl Referral...

Preeclampsia (PE) is a complex, hypertensive disorder of pregnancy, demonstrating considerable variability in maternal symptoms and fetal outcomes. Unfortunately, prior research has not accounted for this variability, resulting in a lack of robust biomarkers and effective treatments for PE. Here, we created a large (N=330) clinically relevant human placental microarray data set, consisting of 7...

Hypertension occupies a unique position in public health care, because it is the major cause of cardiovascular disease and most frequent non-communicable disorder seen primary care globally. The prevalence, treatment, control rates hypertension vary greatly by ethnicity. Such disparities are mostly linked to genetic variances, although lifestyle socioeconomic level may influence behaviours such...

mild (140 to 159/90 to 99 mmhg) or moderate (160 to 179/100 to 109 mmhg) chronic arterial hypertension does not appear to cause headache. whether moderate hypertension predisposes patients to headache at all remains controversial, but there is little evidence that it does. ambulatory blood pressure monitoring in patients with mild and moderate hypertension has shown no convincing relationship b...