As cellular reservoirs, CD16 monocyte subsets play important roles in the progression of HIV infection. Previous studies have shown that highly active antiretroviral therapy (HAART) reduced the percentages of CD14CD16 monocyte subsets, but did not recover the percentages of CD14CD16 subsets. Eighty-four chronic HIV-infected, HAART-naïve individuals and 55 HIV-negative subjects (31 without hyper...

background: disorders of cardiovascular system can cause disability or death, screening is necessary specially in workers who maybe had risk factors. hypertension, hyperlipidemia, obesity, smoking, genetic, exposure to chemicals, fumes, solvents, coldness are non occupational and occupational risk factors. objective was comparison of cardiovascular disorders risk factors between workers in diff...

The detailed pathophysiological mechanisms involved in the progression of hypertriglyceridemia to pancreatitis are little known. Using an animal model we have found that the earliest detectable changes caused by hypertriglyceridemia consist of a selective degeneration of the mitochondria in the exocrine pancreas cells. This supports the view that an excess of free fatty acids deranges the mitoc...

Hypertriglyceridemia is common in children with systemic lupus erythematosus (SLE). A retrospective analysis of the baseline clinical-pathological presentation and treatment outcome (status of lipid profiles) was performed in two children with SLE, who presented with extreme hypertriglyceridemia over a follow-up period of four weeks. The children were treated with prednisolone, mycophenolate mo...

High fructose consumption is associated with insulin resistance and diabetic dyslipidemia, but the underlying mechanism is unclear. We show in hamsters that high fructose feeding stimulated FoxO1 production and promoted its nuclear redistribution in liver, correlating with augmented apoC-III production and impaired triglyceride metabolism. High fructose feeding upregulated PGC-1β and SREBP-1c e...

BACKGROUND We hypothesized that dexamethasone induces hypertriglyceridemia (triglyceride levels >2.82 mmol/L [250 mg/dL]) and increases free fatty acid (FFA) levels and that steroid-induced hypertriglyceridemia is associated with hyperinsulinemia and elevated FFA levels. OBJECTIVE To study the effect of dexamethasone sodium phosphate on lipid metabolism in neonates receiving intravenous lipid...

Severe hypertriglyceridemia is one of the many yet rare risk factors associated with acute pancreatitis. The level of triglycerides plays a crucial role in determining the method and duration of treatment. As with the treatment of other causes of acute pancreatitis, bowel rest, intravenous fluids, and supportive care play a crucial role. However, depending on the degree of hypertriglyceridemia,...