BACKGROUND Stroke constitutes a significant health problem in paediatric population. The impact of childhood stroke can easily be realised in terms of economic, social and psychological burden related to disability of the affected children. The objective of study was to outline the epidemiology and clinical features of stroke in a cohort of Pakistani children and also ascertain the causes and p...

Five cases of thalassaemia minor and 11 symptomless trait carriers have been detected in four Scottish families, only one of which is known to have foreign ancestry. It is suggested that the condition is commoner than was once thought, and that the diagnosis should be considered in any patient with refractory hypochromic anaemia in which the red cells show increased osmotic resistance.

BACKGROUND HIV and anaemia are major health challenges in Africa. Anaemia in HIV-infected individuals is associated with more rapid disease progression and a poorer prognosis if not addressed appropriately. This study aimed at determining the severity and types of anaemia among HIV infected children and its effect on short term response to antiretroviral therapy (ART). METHODS At baseline, cl...

OBJECTIVE The aim of this study was to evaluate the effectiveness of mature red cell and reticulocyte parameters to identify three conditions: iron deficiency anemia, anemia of chronic disease, and anemia of chronic disease associated with absolute iron deficiency. METHODS Peripheral blood cells from 117 adult patients with anemia were classified according to iron status, inflammation, and he...

Lichen sclerosus (LS) is a benign, chronic, inflammatory dermatosis that mainly affects the genitalia and is characterized by pearly-white papules. Its etiology is still unknown; however, genetic factors and autoimmunity have been implicated. It may occur in all age groups and is more prevalent in females than males, with a ratio of 10: 1. LS shows bimodal distribution with a peak incidence in ...

Over an 11 year period, the diagnosis of haemoglobin-H (Hb-H) disease was missed in a Caucasian woman of British stock who first presented with microcytic hypochromic anaemia at the age of 81. The diagnosis was confirmed at the age of 92, when the typical inclusions of Hb-H disease were demonstrated in erythrocytes stained with brilliant cresyl blue, and the presence of Hb-H was documented by h...

The prevalence of Chronic Kidney Disease (CKD) in Indonesia 2013-2018 has increased from 0.2% to 0.38%. Patients with CKD have low erythropoietin, so that the production erythrocytes is disrupted and causes anemia. Anemia includes type normocytic-normochromic. Hypochromic occurs because iron reserves cannot be used process erythropoiesis, resulting decreased synthesis hemoglobin. Erythrocytes w...