Hypoplastic left heart syndrome is a congenital disease which accounts for 8% of all defects. Twin pregnancies have significantly higher risk structural than singleton ones, however the concordance rate has been found to be relatively low, even in monochorionic pregnancies. We describe here favorable evolution monochorionic, diamniotic, twin pregnancy both fetuses were diagnosed with hypoplasti...

Hypoplastic left heart syndrome (HLHS) is one of the most severe congenital heart defects, accounting for 20% to 25% of mortality in infants born with congenital heart disease. In the United States, 2000 infants are born each year with HLHS.1 To date, there is a paucity of studies that define the underlying genetic, molecular and cellular mechanisms of HLHS.2–4 Most cases of HLHS are thought to...

BACKGROUND Hypoplastic left heart syndrome (HLHS) is an etiologically multifactorial congenital heart disease affecting one in 5,000 newborns. Thirty years ago there were no treatment options for this pathology and the natural course of the disease led to death, usually within the first weeks of life. Recently surgical palliative techniques have been developed allowing for a five-year survival ...