although the structure of human t lymphoptropic virus type i (htlv-i) has been known well, the function of some proteins encoded by htlv-i px region is not fully understood. furthermore, the responses of the immune system to htlv-i remain still unknown. most of htlv-i-infected individuals show a strong and persistently activated cytotoxic t-cell (ctl) response to the virus. the frequency of htl...

There are many real problems in which multiple responses should be optimized simultaneously by setting of process variables. One of the common approaches for optimization of multi-response problems is desirability function. In most real cases, there is a correlation structure between responses so ignoring the correlation may lead to mistake results. Hence, in this paper a robust approach based ...

In this paper, tuning of power system stabilizer (PSS) and thyristor controlled series capacitor (TCSC) is studied. The analysis of mode controllability is used to select the effective location for TCSC. The performances of TCSC equipped with a proportional-integral-derivative controller (P-I-D controller) and proportional-integral-derivative power system stabilizer (P-I-D PSS) are investigated...

Type I natural killer T (NKT) cells are innate-like T lymphocytes that recognize glycolipid antigens presented by the MHC class I-like protein CD1d. Agonistic activation of NKT cells leads to rapid pro-inflammatory and immune modulatory cytokine and chemokine responses. This property of NKT cells, in conjunction with their interactions with antigen-presenting cells, controls downstream innate a...

Carbon–carbon bond formation is the core of organic synthesis, in which organometallic reagents play key role forms 1,2-nucleophilic additions, conjugate and transition-metal catalyzed cross-couplings. These reactions have enabled production a wide range molecules our society. Despite enormous power chemical they inherent drawbacks eyes future sustainability. This account summarizes efforts ove...

purpose: evaluation of humoral and cellular immune responses of naturally infected dogs against type i (rcpb) (recombinant cycsteine proteinase b), and ii (rcpa) (recombinant cycsteine proteinase a) recombinant cysteine proteinases and c-terminal extension (cte) of leishmania infantum (l. infantum). materials and methods: in this study, fourteen infected dogs (7 with symptoms, 7 asymptomatics)...

Mutations of Ca(2+)-activated proteases (calpains) cause muscular dystrophies. Nevertheless, the specific role of calpains in Ca(2+) signalling during the onset of dystrophies remains unclear. We investigated Ca(2+) handling in skeletal cells from calpain 3-deficient mice. [Ca(2+)](i) responses to caffeine, a ryanodine receptor (RyR) agonist, were decreased in -/- myotubes and absent in -/- myo...