Polypoidal choroidal vasculopathy (PCV), an oddity shown at fluorescein conferences 35 years ago, is now recognized as a common cause of neovascular maculopathy among thoseolder than50years.1 Its prevalencehasnot increased, but new imaging techniques have revealed its features and ophthalmicconsciousnesshasbeen raised.Randomizedclinical trials that compare treatments, rather than case series, a...

Background and objectives: To study the abnormalities in the choroidal circulation in cases of central serous chorioretinopathy (CSC) and to compare it with fundus fluorescein angiography. Setting and Design: Prospective, interventional and non comparative case series in a tertiary eye care institute. Material and Methods: 40 consecutive cases of CSC were included in the study. A complete clini...

BACKGROUND The aim of this study is to determine the differences in optical coherence tomography angiography (OCTA) features of acute Vogt-Koyanagi-Harada disease (VKH) and acute central serous chorioretinopathy (CSC). Clinical and imaging data of patients with acute CSC and VKH in a tertiary-care institute were analyzed. Multimodal imaging including fluorescein angiography, indocyanine green a...

The 22nd World Computer Chess Championship started on June 27, 2016. Six programs participated in a double round robin tournament, see Table 1 (CPW 2016a-u; Krabbenbos et al., 2016). The tournament took place at Leiden University and was organized by the ICGA, LIACS and LCDS. It was sponsored by Google, Naturalis Biodiversity Center, the municipality of Leiden, Leiden University, its Faculty of...

Purpose. To show the long-term results of intravitreal ranibizumab combined with photodynamic therapy (PDT) for the treatment of polypoidal choroidal vasculopathy (PCV). Methods. We analyzed the progress of two patients for 36 and 58 months, respectively. We only used PDT for the treatment in the area of the active PCV or "hot spot" evident on the indocyanine green angiography (ICGA). The spot ...

A patient complained of photopsia and vision loss in the left eye for two days, with visual acuity of 20/32. Right eye was normal. Funduscopy revealed foveal granularity and gray-white lesions in the posterior pole, mainly temporal to the fovea. The lesions (dots and spots), along with a few other areas surrounding them, showed hyperautofluorescence on autofluorescence imaging. Fluorescein angi...

Polypoidal choroidal vasculopathy (PCV) is a retinal disease involving the choroidal vasculature characterized by the presence of polypoidal lesions with or without branching vascular network best seen on indocyanine green angiography (ICGA). Clinical features of PCV include recurrent subretinal hemorrhage; serosanguineous pigment epithelial detachment, subretinal exudation and serous retinal d...

PURPOSE We assessed the application of the choroidal vascularity index (CVI) in the follow-up of Vogt-Koyanagi-Harada disease (VKH) patients derived from image binarization of enhanced depth imaging optical coherence tomography (EDI-OCT) images with Fiji software. Our secondary objective was to derive the retinochoroidal vascularity index based on en face fundus fluorescein and indocyanine gree...

PURPOSE The purpose of this study was to evaluate the performance of optical coherence tomography angiography (OCTA) in visualizing laser-induced choroidal neovascularization (CNV) in the rodent retina. METHODS Choroidal neovascularization was induced via laser photocoagulation in 2 male Brown Norway rats and 2 male C57BL/6 mice. For qualitative comparison, the animals were imaged in vivo wit...