نتایج جستجو برای: idiopathic parkinson disease
تعداد نتایج: 1538852 فیلتر نتایج به سال:
Parkinson’s disease is the second most common age associated neuron degenerative disorder in developed societies. With the prevalence ranging from 41 per 100000 in the fourth decade of life to over 1900 per 100000 in people over 80 years of age.it characterized clinically by resting tremor, slowness of movement, rigidity and postural instability in the result of progressive loss of dopami...
OBJECTIVE The present study shows the results of a double-blind sham-controlled pilot trial to test whether measurable stimulus-specific functional connectivity changes exist after Automatic Mechanical Peripheral Stimulation (AMPS) in patients with idiopathic Parkinson Disease. METHODS Eleven patients (6 women and 5 men) with idiopathic Parkinson Disease underwent brain fMRI immediately befor...
OBJECTIVES Antidepressants, among the most commonly prescribed medications, trigger symptoms of REM sleep behavior disorder (RBD) in up to 6% of users. Idiopathic RBD is a very strong prodromal marker of Parkinson disease and other synuclein-mediated neurodegenerative syndromes. It is therefore critically important to understand whether antidepressant-associated RBD is an independent pharmacolo...
Patients with Parkinson disease (PD) may have decreased physical activity due to motor deficits. We recently validated the reliability of step activity monitors (SAMs) to accurately count steps in PD, and we wished to use them to evaluate the impact of disease severity on home activity levels in PD. Twenty-six subjects with PD (Hoehn and Yahr disease stage 2-4) were recruited to participate in ...
BACKGROUND Previously, we detected linkage of idiopathic Parkinson disease (PD) to the region on chromosome 6 that contains the Parkin gene (D6S305; logarithm of odds score, 5.47) in families with at least one individual with age at onset younger than 40 years (families with early-onset disease). Further study demonstrated the presence of Parkin mutations in this data set. However, previous cas...
background: there is no documented demographical study on iranian parkinson's disease (pd) patients, so this study was conducted to identify demographic information about patients with pd in iran, and to explore demographical differences between pd patients in iran and other countries. methods: we reviewed medical records of 1656 patients diagnosed with pd, who referred from all parts of iran t...
background and objectives: parkinson's disease (pd) is a common neuropathologic disorder that is caused by degeneration of dopaminergic neurons of dense part of nigra. oxidative stress has been found in the pathophysiology of pd. since α-pinene has strong anti-oxidant effects, the purpose of this research was to study its effects on movement disorders and memory and lipid peroxidation in p...
background & aim:parkinson's disease (pd) is a kind of disorder in the nervous system, which is characterized with multiple movement disorders. factors such as oxidative stress are the most important causes for the degeneration of dopaminergic neurons in the substantia nigra and occurrence of parkinson's disease. thus, medications that have antioxidant functions could be an interestin...
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