Background: Morphine is wildly used as a painkiller in clinics, but causes several side effects such as hyperalgesia, depression and more notably amnesia. Here, we assumed that insulin-like Growth Factor-1 (IGF-1) as a peptide with widespread distribution of receptors in brain regions, especially hippocampus, might be capable to alleviate morphine-induced amnesia. Meth...

As a tool for measuring the aging process, life span has been invaluable in dissecting the genes that modulate longevity. Studies over the past few decades have identified several hundred genes that can modify life span in model organisms such as yeast, worms, and flies. Yet, despite this vast amount of research, we still do not fully understand how the genes that affect life span influence how...

growth hormone and insulin-like growth factor 1 are anabolic hormones which play a vital role in developing body tracts especially in childhood and adolescence years. exercise is a motive which influences gh and igf-1 secretion. today, water sports are highly recommended due to creating delight in children. therefore, the purpose of this study was to examine the effect of eight weeks of water t...

in teleosts the insulin-like growth factor-i, a member of igf system, play an important role in the control of growth and reproduction including metabolism, cell division, oogenesis, final oocyte maturation and secretory activity. this system is controlled by several hormones and metabolic status. serum igf-i, thyroxine (t4) and cortisol levels were studied in two female brood stocks (caught fr...

O presente artigo buscou analisar a viabilidade da regulamentação do imposto sobre grandes fortunas (IGF) com o objetivo de verificar possibilidade isonomia tributária no país. Previsto Art. 153, VIII, CF, sendo competência União, deve ser regulamentado por meio Lei Complementar, ainda não exercida. princípio Isonomia Tributária garante instituição um tributo progressivo, assim como IGF, este q...

Objective(s): The mitogenic effect of the analogous insulin glargine is currently under debate since several clinical studies have raised the possibility that insulin glargine treatment has a carcinogenic potential in different tissues. This study aimed to evaluate the Igf-1r, Insr, and Igf-1 gene expression in colon and liver of streptozotocin-induced diabetic rats in response to insulin glarg...

baluchi sheep is considered as the most common breed in iran, constituting about 30% of total sheep population, approximately 15 million heads. this research was designed to study the incidence of mutation in two loci of igf-i (exon 3) and adrb3 (intron) along with their association with body weight traits in baluchi sheep population. following dna extraction from 190 baluchi sheep, two pairs o...