This paper describes the design and implementation of an OWL 1.1 API, herein referred to as the OWL API . The API is designed to facilitate the manipulation of OWL 1.1 ontologies at a high level of abstraction for use by editors, reasoners and other tools. The API is based on the OWL 1.1 specification and influenced by the experience of designing and using the WonderWeb API and OWL-based applic...

This case study reveals Daniel Webster College’s experience igniting student enthusiasm for the computer sciences by combining complex game development with innovative classroom management techniques during the freshman year. In this paper we discuss CS1 and CS2 game motif exercises which have dramatically accelerated student progress at DWC by stimulating independent study, cooperative learnin...

Igniting thermogenesis within white adipose tissue (i.e., promoting expression and activity of the uncoupling protein UCP1) has attracted much interest. Numerous "browning agents" have now been described (gene ablations, transgenes, food components, drugs, environments, etc.). The implied action of browning agents is that they increase UCP1 through this heat production, leading to slimming. Her...

Our discovery of a novel cytoplasmic domain in HEp-2 cells recognized by the autoimmune serum of a patient led us on a journey into the world of microRNAs (miRNA). Our journey began with the identification and cloning of the novel glycine (G)–tryptophan (W)-rich protein, GW182, and its close interaction with the miRNA-binding protein, argonaute2 (Ago2). Discovering the important relevance of GW...

background: ethical issues are essential components in any piece of research. in fact, they ought to be considered during designing, planning and conducting each research study particularly among the vulnerable. the aim of this paper is to describe and explain some of the ethical issues and challenges faced by a researcher who carried out a research in three malaysian residential homes. materia...