نتایج جستجو برای: imidazoline derivatives
تعداد نتایج: 105684 فیلتر نتایج به سال:
Imidazoline receptors are divided into I(1) and I(2) subtypes. I(1)-imidazoline receptors are distributed in the heart and are upregulated during hypertension or heart failure. The aim of this study was to define the possible role of I(1)-imidazoline receptors in the regulation of atrial natriuretic peptide (ANP) release in hypertrophied atria. Experiments were performed on isolated, perfused, ...
Unexpected colloidal assemblies form in aqueous mixtures of sodium dodecylbenzenesulfonate (SDBS) with the following imidazoline compounds: 2,2'-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride (V-44, which is a commonly used free-radical initiator), 2,2'-tetramethylenedi-2-imidazoline (TMI), and the main recombination product (RP) from the decomposition of V-44. All of these imidazoline co...
Imidazoline receptor proteins are decreased in the hippocampus of individuals with major depression.
BACKGROUND A downregulation of I(2)-imidazoline binding sites has been reported in frontal cortices of depressed suicide victims, according to I(2)-radioligand binding and confirmed by Western blotting. We now report Western blots of imidazoline receptor proteins in hippocampi of subjects with and without depression at the time of death. METHODS Postmortem diagnoses were obtained from 17 case...
Inhibition performances of imidazoline derivatives with different alkyl chain length for carbon steel in H2S acid solutions has been studied by polarization curves, AC impedance measurements, current transient, Atomic Force Microscopy (AFM) and Density Functional Theory (DFT) techniques. Results showed that the inhibition occurs through adsorption of the inhibitors molecules ...
BACKGROUND Dexmedetomidine (Precedex; Abbott Laboratories, Abbott Park, IL) is a selective alpha2-adrenergic agonist that also has affinity for imidazoline receptors. In clinical studies, dexmedetomidine has sedative effects and impairs memory, but the action of dexmedetomidine on synaptic plasticity in the brain has yet to be established. In the present study, the authors investigated the effe...
In the title compound, C(15)H(21)N(2)O(5), the imidazoline ring displays a twisted conformation. The mean plane of the imidazoline ring makes a dihedral angle of 22.55 (5)° with the benzene ring. In the crystal, O-H⋯O and C-H⋯O hydrogen bonds link the mol-ecules into a layer parallel to the bc plane.
The compound 2-(2-benzofuranyl)-2-imidazoline (2-BFI) is a 2-imidazoline derivative that selectively inhibits the in vitro activity of monoamine oxidase-A and it is also an imidazoline I(2) agonist. However, the antidepressant potential of this compound and its mechanism of action have not been well defined. Therefore, in this study we investigated the antidepressant-like effect of 2-BFI in mic...
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