T his issue of the Journal is mainly devoted to a specific, crucial topic in the field of histochemical research: how in situ technologies can be exploited to study tissue samples from patients with specific diseases. The final goal is on one hand a more accurate diagnosis; on the other, the identification of specific features that can: i) be followed and compared at different time points ii) p...

This supplement to the "International Review of Cytology" is entitled "Aspects of Nuclear Structure and Function." Thus it is strange that the first article in the series, "Comparative Aspects of the Female Gamete," contains but one page of text on the oocyte nucleus and one on the nuclear envelope. This quasi-philosophical review of studies on oocyte morphology falls short of being well writte...

A report of a woman in her fifties with Schnyder's crystalline stromal dystrophy is presented. There is no personal or family history of hypercholesterolaemia. A full thickness corneal disc was removed before grafting and examined by polarised light, histochemistry, and electron microscopy. Specific lipid histochemical methods showed deposits of cholesterol and cholesterol ester in the superfic...