Background: Alopecia areata (AA) is an immune-mediated form of hair loss that affects all ages and both sexes.Paraoxonase 1 (PON1) esterase enzyme has lipophilic antioxidant power; it one the endogenousfree-radical-scavenging systems in human body. This work was to detect serum PON1 level patients withalopecia areata.Methods: 60 subjects, 30 AA controls. Full history, general local clinical exa...

background and objectives: complement proteins are some of the most important plasma proteins of the innate immune system. impaired immune function is reported in subjects who are iron deficient, and there are documents that these patients are prone to infection. this study was conducted to show whether serum c3 and c4 complement change in adult nonpregnant female with iron deficient anemia or ...

polyclonal anti-thymocyte globulin (atg) is used as an immunosuppressive agent in the treatment of aplastic anemia (aa). serum sickness is a recognized side effect of atg. we observed abnormal skin manifestation in patient with aplastic anemia who had been treated with atg. we conclude that abnormal immune function caused by aplastic anemia and atg and corticosteroids may aggravate the signs of...

Background: Cancer immunotherapy is a promising strategy for cancer treatment. In this strategy,   the immune system is triggered to destroy cancer cells. IL-2 is an important factor in passive cancer immunotherapy that helps modulating some important immune functions. One of the IL-2 limitations is low serum half-life; therefore, repetitive high doses of the injections are required t...

Antigenic variants of influenza A virus strains emerge on serial passage in ovo in the presence of immune serum against different but related strains. An old laboratory strain (PR8) which had been through hundreds of animal passages was as readily modified by this procedure as recently recovered strains. Such variants apparently can be obtained at will and show antigenic patterns which are repr...

Johnson, Russell C. (University of Minnesota, Minneapolis), and Louis H. Muschel. Antileptospiral activity of serum. I. Normal and immune serum. J. Bacteriol. 91:1403-1409. 1966.-Normal serum was found to exert a leptospiricidal effect, mediated by the complement system, against the nonpathogenic leptospires. Although resistant to normal serum, the pathogenic serotypes were susceptible to antis...

1. Immune serum instilled intranasally in guinea pigs has protected them from infection with lethal amounts of pseudorabies virus by the nasal route. The same effect was obtained in mice with immune serum against the virus of equine encephalomyelitis (Eastern strain). 2. The protective effect of the immune serum in the nose begins at the time of instillation, is still evident 5 hours later, and...

The objective of the study was to compare the effects of antibiotic virginiamycin, probiotic Protexin® and Plantago major L. (plantain) on performance, serum metabolites, immune response, and the ileal microbial population of broilers. The experiment was carried out with a total of 200 day-old male Ross 308 broiler chickens in a completely randomized design. Chickens were allocated to five grou...