This vignette describes the R hglm package via a series of applications that may be of interest to applied scientists. The hglm package implements the estimation algorithm for hierarchical generalized linear models. The package fits generalized linear models with random effects, where the random effect may come from a conjugate exponential-family distribution (Gaussian, Gamma, Beta or inverse-G...

This study investigated the antioxidant and immunomodulatory potential of six blue whiting soluble protein hydrolysates (BWSPHs, BW-SPH-A to -F) their simulated gastrointestinal digests (SGID, BW-SPH-A-GI -F-GI) in murine RAW264.7 macrophages. Hydrolysate BW-SPH-A, both pre- post-SGID, increased endogenous glutathione (GSH) tert-butylhydroperoxide (tBOOH)-treated cells reduced reactive oxygen s...

We investigated the anti-tumor effects of a dry powder preparation of the antlered form of Ganoderma lucidum (G. lucidum AF, rokkaku-reishi in Japanese), a variant type of G. lucidum, not only in allogeneic Sarcoma 180-bearing ddY mice, but also in syngeneic MM 46-bearing C3H/He mice. G. lucidum AF inhibited tumor growth and elongated the life span when orally administered to mice by free-feedi...

Chitosan and its oligosaccharides, which are known to possess multiple functional properties, have attracted considerable interest due to their biological activities and potential applications in the food, pharmaceutical, agricultural and environmental industries. Many researchers have focused on chitosan as a potential source of bioactive materials in the past few decades. This review focuses ...

Sustainable fish farming activities are a hope for all cultivators. Suitable and stable environmental conditions important factors the sustainability of to grow, reproduce, avoid stress disease. Providing balanced diet is one that must be considered. Diets equipped with additives have been in great demand by researchers field aquaculture, which chitosan. Chitosan (β-(1-4)-N-acetyl-D-glucosamine...

The nutritional jujube ( Ziziphus jujube Mill.) fruit belonging to the Rhamnaceous family grows mostly in Europe, southern and eastern Asia, and Australia, especially the inland region of northern China. Jujube has a long history of usage as a fruit and remedy. The main biologically active components are vitamin C, phenolics, flavonoids, triterpenic acids, and polysaccharides. Recent phytochemi...

Shift work which causes circadian disruption is an established cancer risk factor. A large body of experimental and epidemiological data proves that exposure to light at night promotes carcinogenesis in various tissues and accelerates aging [1-3]. Artificial or natural light through master clock located in suprachiasmatic nuclei of hypothalamus suppresses night peak of melatonin synthesis in th...