Prostaglandins (PGs), derivatives of arachidonic acid, play an indispensable role in embryo implantation. PGs have been reported to participate in the increase in vascular permeability, stromal decidualization, blastocyst growth and development, leukocyte recruitment, embryo transport, trophoblast invasion, and extracellular matrix remodeling during implantation. Deranged PGs syntheses and acti...

A critical point in mammalian development is when the early embryo implants into its mother's uterus. This event has historically been difficult to study due to the fact that it occurs within the maternal tissue and therefore is hidden from view. In this review, we discuss how the mouse embryo is prepared for implantation and the molecular mechanisms involved in directing and coordinating this ...

the success rate of reproductive treatment methods depends on many different factors. the most important and discussed ones in the literature are maternal age, the causes of infertility, the ovarian response to stimulation, the influence of the male factor and sperm quality, embryo quality and the various uterine pathologies. some couples fail repeatedly after transferring good quality embryos ...

Background: Vitrification and warming of blastocysts is an established procedure for the preservation of embryos during IVF. Vitrification is so successful that it allows for elective single embryo transfer (eSET) to be performed routinely, since the frozen embryos will be available with high implantation potential if the fresh embryo fails. Comprehensive chromosome screening (CCS) is also a pr...

The activity of mouse endometrial alkaline phosphatase after hyperstimulation and progesterone injection at the implantation time Alkaline phosphatase (ALP) of endometrium may play a critical function in the development and implantation of embryo. The aim of this study was to determine the localization of endometrial ALP activity after hyperstimulation and progesterone injection. Thirty adult f...

OBJECTIVE Embryo implantation is directly affected by genes related to uterine receptivity. Studies have demonstrated the important roles of miRNAs in the regulation of gene expression. Our early miRNA chip analyses revealed that the mmu-miR-141 expression in endometrial tissue is lower after embryo implantation than before it. However, the possible roles of miR-141 in embryo implantation have ...

Background: According to Ayurveda, Ambu is one of the four essential factors Garbhasambhav Samugri for formation and development embryo. The word means nutrients growth embryo which it receives from mother. modern science, during implantation, its endometrium. Though some women have normal endometrial thickness, pattern, morphology, still they are unable get impregnated. During peri-implantatio...

BACKGROUND Proprotein convertase 5/6 (PC5/6) is critical for embryo implantation in women, regulating both uterine epithelial receptivity and stromal cell decidualization. PC5/6 is likewise essential for implantation in mice, but involved only in decidualization. An alternative animal model is required to address the function of PC5/6 in the uterine epithelium. This study aimed to establish whe...

BACKGROUND We aimed to assess the validity of a theoretical mathematical model to predict the pregnancy rate and the multiple pregnancy rate in IVF/oocyte donation programmes on the basis of the implantation rate and the number of transferred embryos. METHODS A total of 1835 embryo transfers corresponding to three different programmes in two centres with different implantation rates were anal...