OSPF is a link-state intra-domain routing protocol used in IP networks. OSPF behavior over demand circuits (DC) is optimized in RFC 1793 to minimize the amount of overhead traffic. A part of the OSPF demand circuit extensions is the Hello suppression mechanism. This technique allows a demand circuit to go down when no interesting traffic is going through the link. However, it also introduces a ...

Ends of human chromosomes called telomeres are essential for their structural and functional stability [1]. However, these DNA structures designed to function via a plethora of proteins and RNA molecules that bind them, encounter progressive shortening with each cell division due to the end replication problem. Terc, a long non coding (lnc)RNA and the reverse transcriptase TERT which uses Terc ...

Unsafe abortion is a significant but preventable cause of global maternal mortality and morbidity. Zambia has among the most liberal abortion laws in sub-Saharan Africa, however this alone does not guarantee access to safe abortion, and 30% of maternal mortality is attributable to unsafe procedures. Too little is known about the pathways women take to reach abortion services in such resource-po...

In the present study, we developed a method for detecting sequences whose similarity to a target sequence is statistically significant and we examined the distribution of these sequences in the E. coli K-12 genome. Target sequences examined are as follows: (i) short repeat: Crossover hot-spot instigator (Chi) sequence, replication termination (Ter) sequence, and DnaA binding sequence (DnaA box)...

Chlorothiazide sodium for injection, USP is a sterile lyophilized white powder and is supplied in a vial containing: Chlorothiazide sodium equivalent to chlorothiazide 500 mg, and the inactive ingredient mannitol 250 mg with sodium hydroxide to adjust pH. Chlorothiazide is a diuretic and antihypertensive. It is 6-chloro-2H-1,2,4-benzothiadiazine-7sulfonamide 1,1-dioxide, and its structural form...