Work-related asthma in aluminium potroom workers, is reviewed and discussed, mainly on the basis of own investigations. The occurrence of work-related asthma has been shown to be associated with the duration of potroom employment, although the prevalence of asthmatic symptoms is not significantly different from that of the general population. Typical manifestations of occupational asthma are de...

A pharmaceutical worker developed asthma when exposed to hydralazine, an antihypertensive drug. The diagnosis of occupational asthma was supported by specific inhalation challenges, which produced a late asthmatic reaction and an increase in bronchial responsiveness. No evidence of an IgE or an IgG dependent mechanism could be found.

Six workers exposed as bystanders to heated triglycidyl isocyanurate (TGIC) developed occupational asthma confirmed by serial peak expiratory flow measurement and Oasys analysis. Specific inhalation challenge testing resulted in late or dual asthmatic reactions to heated TGIC in four of four tested and was negative in three control asthmatics. One worker tested only with unheated TGIC had a neg...

Asthma is one of the most common noninfectious chronic diseases characterized by type II inflammation. This study aimed to investigate effects molecular hydrogen on pathogenesis asthma. OVA sensitized asthma mouse model and house dust mite treated 16HBE cellular were established hydrogen/oxygen mixture was used treat asthmatic mice cells. Serum BALF cytokines measured with specific ELISA assays...

A retrospective investigation of 86 asthmatic subjects defined clinical features of irritant-induced asthma and assessed the contributory role of an allergic predisposition. Three categories of asthma were evaluated: (1) occupational asthma due to a sensitizer (11 subjects, 13%); (2) irritant-induced asthma (54 persons, 63%); and (3) not occupational/environmental exposurerelated asthma (21 sub...

   Cromolyn sodium, a mast cell stabilizing agent, provides an immediate protective effect against the exercise-induced bronchoconstriction while being used before the exercise. However, cromolyn is ineffective in reversing asthmatic bronchospasm; it is used as a maintenance therapy and has a prophylactic role in chronic asthma.    The purpose of this study was to determine the extent of change...

Subcutaneous immunotherapy (SCIT) is a classic form of allergen-specific that used to treat birch pollen induced allergic asthma. To investigate the underlying molecular mechanisms SCIT, we aimed profile lung samples explore changes in differential proteome before and after SCIT mice with Fresh lungs were collected from three groups female BALB/c mice: 1) control mice, 2) pollen-induced 3) SCIT...