Microfluidics has experienced massive growth in the past two decades, and especially with advances in rapid prototyping researchers have explored a multitude of channel structures, fluid and particle mixtures, and integration with electrical and optical systems towards solving problems in healthcare, biological and chemical analysis, materials synthesis, and other emerging areas that can benefi...

A scheme is presented to actively control particulate position in inertial microfluidics. The unilateral slip boundary applied regulate the velocity distribution of flow field microchannel, thus vertical equilibrium particle can be changed with length. Three kinds typical particles, namely circular, elliptical, and rectangular, are simulated. results demonstrate that positions manipulated withi...

This paper presents an inertial microfluidic device with a simple serpentine micro-channel to continuously separate particles with high performance. Separation of micro/nano-particles has a variety of potential applications in biomedicine and industry. Among the existing separation technologies, a label-free technique without the use of antibody affinity, filter or centrifugation is highly desi...

MICROFLUIDICS Wong Cheng Lee, Ali Asgar. S. Bhagat, Sha Huang, Krystyn J. Van Vliet, Jongyoon Han, Chwee Teck Lim BioSystems and Micromechanics (BioSyM) IRG, Singapore-MIT Alliance for Research and Technology (SMART) Centre, SINGAPORE NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, SINGAPORE Department of Electrical Engineering & Computer Science,...

Even though microfluidics has been successfully used in minimizing complicated and onerous processes, the pumping and tubing systems used with it are yet undeveloped and need immediate development. The present study developed a fluttering bar-driven micropump, mounted on a polydimethylsiloxane microfluidic system. The pump consists of a rectangular ferromagnetic bar and a fan-shaped chamber wit...

We present an inertial microfluidic platform for rapid, multiplexed affinity purification of proteins and cells from complex mixtures. Beads of different sizes, coated with different bait molecules bind specific proteins or cells in a single reaction step and the bound targets are then size-sorted by flowing in a spiral microchannel. We use this scheme to simultaneously purify antibodies specif...

Inertial microfluidics is a promising tool for many lab-on-a-chip applications. Particles in channel flows with Reynolds numbers above one undergo cross-streamline migration to a discrete set of equilibrium positions in square and rectangular channel cross sections. This effect has been used extensively for particle sorting and the analysis of particle properties. Using the lattice Boltzmann me...