Introduction: Recent studies demonstrated that cannabidiol had neuroprotective property. Thereis some evidence about effective role of cannabidiol in reducing ischemic damages. It has been reported that infarct size is influenced by various factors after MCAO, including inflammatory factors. The aim of the present study was to evaluate the effect of cannabidiol on infarction volume and correlat...

Although echocardiography has been used in rats, few studies have determined its efficacy for estimating myocardial infarct size. Our objective was to estimate the myocardial infarct size, and to evaluate anatomic and functional variables of the left ventricle. Myocardial infarction was produced in 43 female Wistar rats by ligature of the left coronary artery. Echocardiography was performed 5 w...

Patients suffering an acute myocardial infarction routinely receive morphine and NSAIDs alone or in combination. However, the importance of the dose, timing or the combined administration of both on infarct size reduction has not been assessed. Additionally, it is not known if morphine or NSAIDs require 12-lipoxygenase (12-LO) to mediate infarct size reduction as previously found for ischemic p...

objective(s) dracocephalum moldavica (d. moldavica) have been traditionally used as a cardiotonic agent in the folk medicine of some regions of iran. in the present study, effects of total extract of d. moldavica on ischemia/reperfusion induced arrhythmias and infarct size investigated in isolated rat heart. materials and methods the isolated hearts were mounted on a langendorff apparatus then ...

Background Cardiac magnetic resonance imaging (CMR) with delayed gadolinium enhancement (DE) enables accurate infarct size measurement, however, the evaluation of infarct size using a threshold method is time consuming and relies on accurate placement of normal regions of interest and manual delineation of the infarct size. The purpose of the study was to analyze the accuracy and expenditure of...